Neelja Singhal
Dr., University of Delhi South Campus New Delhi
Location: India
Consulting Services
Areas Of Interest
Professional Narrative
Employment
Education
Referees
Prof J S Virdi, University of Delhi South Campus.
“Prof and HOD”
Dr Deepa Bisht, National JALMA Inst for Leprosy & Other Mycobacterial Diseases.
“Dr.”
Publications
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$ Corresponding Author # Equal Contribution
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$ 43 |
Singh NS, Singhal N, Kumar M, Virdi JS (2022) Public health implications of plasmid-mediated quinolone and aminoglycoside resistance genes in Escherichia coli inhabiting a major anthropogenic river of India. Epidemiol Infect. [PMID: 35343419] |
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$ 42. |
Pandey D, Singhal N, Kumar, M (2021) Investigating the OXA Variants of ESKAPE Pathogens. Antibiotics (Basel, Switzerland), 10(12), 1539. [PMID: 34943751] |
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41. |
Singhal N, Garg A, Singh N, Gulati P, Kumar M, Goel M (2021) Efficacy of signal peptide predictors in identifying signal peptides in the experimental secretome of Picrophilous torridus, a thermoacidophilic archaeon. PLoS One 16(8):e0255826. [PMID: 34358261] |
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$ 40. |
Singhal N, Singh NS, Mohanty S, Kumar M, Virdi JS (2021) Rhizospheric Lactobacillus plantarum (Lactiplantibacillus plantarum) strains exhibit bile salt hydrolysis, hypocholestrolemic and probiotic capabilities in vitro. Sci Rep 11(1):15288. [PMID: 34315963] |
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$ 39. |
Singh NS, Singhal N, Kumar M, Virdi JS (2021) Exploring the genetic mechanisms underlying amoxicillin-clavulanate resistance in waterborne Escherichia coli. Infect Gen Evol 90:104767. [PMID: 33581330] |
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$ 38. |
Singh NS, Singhal N, Kumar M, Virdi JS (2021) High prevalence of drug resistance and class 1 integrons in Escherichia coli isolated from river Yamuna, India: a serious public health risk. Front Microbiol. [PMID: 33633708] |
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37. |
Singhal N, Sharma A, Aswal M, Singh N, Kumar M, Goel M (2021) Identification of binding partners of CsaA - an archaeal chaperonic protein of Picrophilus torridus. Protein Pept Lett 2021; 28(6):675-679. .[PMID: 33243110] |
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$36. |
Singhal N, Sharma D, Kumar M, Bish D, Virdi JS (2020) Comparative proteomics of commensal and pathogenic strains of Escherichia coli. Protein Pept Lett 27(11):1171-1177 [PMID: 32416668] |
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$ 35. |
Garg A, Singhal N, Kumar M (2020) Discerning novel drug targets for treating Mycobacterium avium ss. paratuberculosis-associated autoimmune disorders: an in silico approach. Brief Bioinform; bbaa195 [PMID: 32895696] |
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$ 34. |
Singhal N, Pandey D, Singh NS, Kumar M, Virdi JS (2020) Exploring the genetic determinants underlying the differential production of an inducible chromosomal cephalosporinase-BlaB in Yersinia enterocolitica biotypes 1A, 1B, 2 and 4. Sci Rep 10(1):10167 [PMID: 32576927] |
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33. |
Pandey D, Kumari B, Singhal N, Kumar M (2020) BacEffluxPred: A two-tier system to predict and categorize bacterial efflux mediated antibiotic resistance proteins. Sci Rep 10(1):9287 [PMID: 32518231] |
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32. |
Garg A, Singhal N, Kumar R, Kumar M (2020) mRNALoc: a novel machine-learning based in-silico tool to predict mRNA subcellular localization. Nucleic Acids Res 48(W1):W239-W243 [PMID: 32421834] |
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31. |
Singhal N, Sharma A, Kumari S, Garg A, Rai R, Singh N, Kumar M, Goel M (2020) Biophysical and biochemical characterization of nascent polypeptide-associated complex of Picrophilus torridus and elucidation of its interacting Partners. Front Microbiol 11:915 [PMID: 32528429] |
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30. |
Aswal M, Garg A, Singhal N, Kumar M (2020) Comparative in-silico proteomic analysis discerns potential granuloma proteins of Yersinia pseudotuberculosis. Sci Rep 10(1):3036 [PMID: 32080254] |
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# 29. |
Virdi JS, Singhal N, Maurya AK, Ramamurthy T, Singh P, Singhvi N (2019) Medical Microbiology in India: The Recent Developments in the Basic Research, Diagnostics and Vaccines. Proceedings of the Indian National Science Academy 85 (4), 1025-1037 |
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$ 28. |
Singhal N, Maurya AK, Mohanti S, Kumar M, Virdi JS (2019) Evaluation of bile salt hydrolases, cholesterol-lowering capabilities and probiotic potential of Enterococcus faecium isolated from rhizosphere. Frontiers Microbiol 10:157 [PMID: 31379762] |
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27. |
Singhal N, Singh NS, Maurya AK, Virdi JS (2019) Virulence-associated traits and in vitro biofilm-forming ability of Escherichia coli isolated from a major river traversing Northern India. Environ Sci Pollut Res Int. 26(21):21304-21311 [PMID: 31124069] |
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$ 26. |
Singhal N, Maurya AK, Singh NS, Kumar M, Virdi JS (2019) Antimicrobial resistance and its relationship with biofilm production and virulence-related factors in Yersinia enterocolitica biotype 1A. Heliyon 5 (5), e01777 [PMCID: PMC6535577] |
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25. |
Singhal N, Pandey D, Kumar M, Virdi JS (2019) Molecular analysis of ampR and ampD to understand variability in inducible expression of "BlaB-like" cephalosporinase in Yersinia enterocolitica biotype 1A.Gene. 704:25-30. [PMID:30980942] |
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24. |
Singhal N, Pandey D, Singh NS, Kumar M, Virdi JS (2019) ampD homologs in biotypes of Yersinia enterocolitica: implications in regulation of chromosomal AmpC-type cephalosporinases. Infect Genet Evol. 69:211-215.[ PMID: 30710654] |
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23. |
Singhal N, Pandey D, Singh NS, Kumar M, Virdi JS (2019) Molecular characteristics of “BlaB-like” chromosomal inducible cephalosporinase of Yersinia enterocolitica biotype 1A strains. Microb Drug Res. 25(6):824-829. [PMID: 30817214] |
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22. |
Singhal N, Singh NS, Mohanty S, Singh P, Virdi JS (2019) Evaluation of probiotic characteristics of lactic acid bacteria isolated from two commercial preparations available in Indian market. Indian J Microbiol 59(1):112-115. [PMID:30728640] |
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21. |
Singhal N, Maurya AK, Virdi JS (2019) Bacterial Whole Cell Protein Profiling: Methodology, Applications and Constraints. Current Proteomics. 16 (2): 102-109. |
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20. |
Garg A, Kumari B, Singhal N, Kumar M (2019) Using molecular-mimicry-inducing pathways of pathogens as novel drug targets. Drug Discovery Today. 24(9):1943-1952. doi: 10.1016/j.drudis.2018.10.010 [PMID:30366058] |
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19. |
Singh NS, Singhal N, Virdi JS (2018) Genetic environment of blaTEM-1, blaCTX-M-15, blaCMY-42 and characterization of integrons of Escherichia coli isolated from an Indian urban aquatic environment. Frontiers Microbiol 9:382. [PMID: 29563901] |
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18. |
Singhal N, Kumar M and Virdi JS (2016) MALDI-TOF MS in clinical parasitology: applications, constraints and prospects. Parasitology 8:1-10. [PMID: 27387025] |
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17. |
Singhal N, Kumar M and Virdi JS (2016) Resistance to amoxicillin-clavulanate and its relation to virulence-related factors in Yersinia enterocolitica biovar 1A. Ind J Med Microbiol 34(1): 85-87. [PMID: 26776125] |
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16. |
Singhal N, Kumar M, Sharma D and Bisht D (2016) Comparative protein profiling of intraphagoasomal expressed proteins of M.bovis BCG. Proteins Peptide Lett 23(1):51-4 [PMID: 26548863] |
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15. |
Singhal N, Kumar M, Kanaujjia PK and Virdi JS (2015) MALDI-TOF mass spectrometry: An emerging technology for microbial identification and diagnosis. Frontiers Microbiol 6:791. [PMID: 26300860] |
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14. |
Singhal N, Srivastava A, Kumar M and Virdi JS (2015) Structural variabilities in β-lactamase (blaA) of different biovars of Yersinia enterocolitica: implications for β-lactam antibiotic and β-lactamase inhibitor susceptibilities. PloS One 10(4):e0123564.[PMID: 25919756] |
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13. |
Kanaujia PK, Bajaj P, Kumar S, Singhal N, Virdi JS (2015). Proteomic analysis of Yersinia enterocolitica biovar 1A under iron-rich and iron-poor conditions indicate existence of efficiently regulated mechanisms of iron homeostasis. J Proteomics 124:39-49. [PMID: 25913300] |
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12. |
Singhal N, Kumar M and Virdi JS (2014) Molecular analysis of b-Lactamase genes to understand their differential of Yersinia expression in strains enterocolitica Biotype 1A. Nature Sci Rep 4: 5270. [PMID: 24920253] |
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11. |
Srivastava A, Singhal N, Goel M, Virdi JS, Kumar M. (2014). CBMAR: a comprehensive β-lactamase molecular annotation resource. Database (Oxford). 2014 Dec 3;2014: bau111. [PMID: 25475113] |
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10. |
Srivastava A, Singhal N, Goel M, Virdi JS, Kumar M (2014) Identification of Family Specific Fingerprints in β-lactamase Families. Sci World J. 2014:980572. [PMID: 24678282] |
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9. |
Singhal N, Sharma P, Kumar M, Joshi B and Bisht D (2012) Analysis of intracellular expressed proteins of Mycobacterium tuberculosis clinical isolates. Proteome Sci. 10: 14 [PMID: 22375954] |
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8. |
Singhal N, Sharma P, Kumar B, Sengupta U, Venkatesan K and Bisht D (2010) An in vitro model system to study proteins expressed during interaction of mycobacterium with murine macrophages. Adv Biosci Biotechnol 1: 180. |
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7. |
Singhal N, Bisht D and Joshi B (2010) Immunoprophylaxis of tuberculosis: An update of emerging trends. Arch Immunol Ther Exp (Warsz) 58: 97. [PMID: 20140756] |
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6. |
Sharma P, Kumar B, Singhal N, Katoch VM, Venkatesan K, Chauhan DS and Bisht D (2010) Streptomycin induced protein expression analysis in Mycobacterium tuberculosis by two-dimensional gel electrophoresis and mass spectrometry. Indian J Med Res 132: 400. [PMID: 20966518] |
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5. |
Sharma P, Kumar B, Gupta Y, Singhal N, Katoch VM, Venkatesan K and Bisht D (2010) Proteomic analysis of streptomycin resistant and sensitive clinical isolates of Mycobacterium tuberculosis. Proteome Sci 18: 59.[ PMID: 21083941I] |
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4. |
Kumar G, Shankar H, Bisht D, Sharma P, Singhal N, Katoch VM and Joshi B (2010) A simple and rapid method of sample preparation from culture filtrate of M. tuberculosis for two-dimensional gel electrophoresis. Braz J Microbiol 41: 295. [PMID: 24031494] |
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3. |
Bisht D, Singhal N, Sharma P and Venkatesan K (2007) An improved sample preparation method for analysing mycobacterial proteins in two-dimensional gels. Biochemistry (Mosc) 72: 672. [PMID: 17630913] |
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2. |
Bisht D, Singhal N, Sharma P and Venkatesan K (2006) Analysis of mycobacterial strains by two-dimensional gel electrophoresis. J Commun Dis 38: 255. [PMID: 17373357] |
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1. |
Gupta AK, Chauhan DS, Srivastava K, Das R, Batra S, Mittal M, Goswami P, Singhal N, Sharma VD, Venkatesan K, Hasnain S and Katoch VM (2006) Estimation of efflux mediated multi-drug resistance and its correlation with expression levels of two major efflux pumps in mycobacteria. J Commun Dis 38: 246. [PMID: 17373356] |
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Book Chapter |
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1. |
Singhal N, Sharma S, Singh NS, Bajaj P, Virdi JS (2013) Characteristics of β-lactamases and their genes in Yersinia enterocolitica isolated from India In: Antimicrobial Resistance: A Cause for Global Concern (Rubina Lawrence, Ebenezer Jeyakumar, George Thomas) Narosa Publishing House Pvt. Ltd. New Delhi, pp 37-49. ISBN No.978-81-8487-249-1 |
Grants,Awards and Certifications
Grants :
2015-2018: Early Career Research Award by Science & Engineering Research Board (DST) for project, Using antibiotic resistance genes for developing a rapid method for detection of food- and water-borne pathogens in Dept. of Microbiology, University of Delhi South Campus (Budget: 32,30,000 INR)
2018: International travel grant by Science & Engineering Research Board to attend the 28th European Congress of Clinical Microbiology & Infectious Diseases held at Madrid, Spain from 21st-24th April, 2018.
2016: Team member of UDSC-AMR team which won the International Longitude Prize Discovery Award at Royal Society of London Nov, 2016 (supported by NESTA, Innovate-UK and BIRAC, DBT, India).
2016: Full scholarship to attend the UK-India workshop on Antimicrobial Resistance by the British Council and the Royal Society of Chemistry under Newton Link Research Grants.
Awards & Prizes :
2019: Invited for International workshop on Antimicrobial Resistance Databases (AMR DB) organised by the Joint Research Centre (JRC) of the European Commission, held at Varano Borghi, Italy on 22nd May 2019.
2018: International travel grant by Science & Engineering Research Board to attend the 28th European Congress of Clinical Microbiology & Infectious Diseases held at Madrid, Spain from 21st-24th April, 2018.
2016: Team member of UDSC-AMR team which won the International Longitude Prize Discovery Award at Royal Society of London Nov, 2016 (supported by NESTA, Innovate-UK and BIRAC, DBT, India).
2016: Full scholarship to attend the UK-India workshop on Antimicrobial Resistance by the British Council and the Royal Society of Chemistry under Newton Link Research Grants.
2011: DBT-Research Associateship in Biotechnology & Life Sciences, Dept of Biotechnology, New Delhi (not availed).
2011: UGC-Dr. D. S. Kothari Postdoctoral Fellowship by University Grants Commission.
2007: Senior Research Fellowship, Council of Scientific and Industrial Research-University Grants Commission, New Delhi.
2005: Junior Research Fellowship, Council of Scientific and Industrial Research-University Grants Commission, New Delhi.
2004: Scored 95.91 percentile (All India Rank 191) in ‘Graduate Aptitude Test in Engineering’ (GATE) conducted by Indian Institute of Science, Bangalore.
2003: Qualified CSIR-UGC/NET (National Eligibility Test) conducted jointly by the Council of Scientific and Industrial Research (CSIR) and University Grants Commission (UGC), New Delhi.
2004: Qualified Indian Council of Medical Research Junior Research Fellowship exam (ICMR-J.R.F).
2004: Qualified exam conducted by Bhabha Atomic Research Centre for recruitment of scientific officers and called for interview.
Awarded first prize in the inter college general knowledge quiz competition held at Dr. B.R. Ambedkar University Agra.
A number of prizes and awards in curricular and co-curricular activities at school and college level.
