Meredith Gregory ksander
Harvard Medical School Assistant Professor of Ophthalmology
Location: United States
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Dr. Gregory-Ksander has a longstanding interest in how age-related changes in immune privilege and subsequent inflammation contributes to the development of ocular disease. The current research in Dr. Gregory-Ksander’s lab at Schepens Eye Research Institute at Mass. Eye and Ear is specifically focused on how age-related changes in immune privilege and subsequent inflammation contributes to the development of glaucoma and age-related macular degeneration (AMD). Using animal models of glaucoma and AMD, Dr. Gregory-Ksander has identified Fas ligand (FasL) and the NLRP3 inflammasoma as two critical mediators of ocular inflammation and current studies focus on how age-related changes in FasL and the NLRP3 inflammasome contribute to the development of inflammation associated with glaucoma and AMD.
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