Kannan Sridharan
Associate Professor, Arabian Gulf University
Location: Bahrain
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I am a Clinical Pharmacologist with training and publishing experience in the areas of therapeutics, clinical pharmacokinetics, clinical trials, biomarkers, evidence based medicine, pharmacogenetics, meta analysis, systematic reviews. I have obtained grants close to 200,000 USD and published over 160 articles. Recently, I was also mentioned as one of the top 2% scientist in the field of Pharmacology/Clinical Pharmacology by Stanford scientists.
Employment
Education
Referees
Publications
2021:
137. Sridharan K, Al Jufairi M, Al Segai O, et al. Biomarkers in neonates receiving potential nephrotoxic drugs. Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):7078-7088. doi: 10.26355/eurrev_202111_27260.
136. Abdulwahab H, Aljishi M, Sultan A, Al-Kafaji G, Sridharan K, Bakhiet M, Taha S. Whole blood transcriptomic analysis reveals PLSCR4 as a potential marker for vaso-occlusive crises in sickle cell disease. Sci Rep. 2021 Nov 12;11(1):22199. doi: 10.1038/s41598-021-01702-8.
135. Lazarus JV, Mark HE, Villota-Rivas M, Palayew A, …. Sridharan K; NAFLD policy review collaborators. The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge? J Hepatol. 2021 Dec 8:S0168-8278(21)02168-1.
134. Lazarus JV, Mark HE, Anstee QM, …. Sridharan K; NAFLD Consensus Consortium. Advancing the global public health agenda for NAFLD: a consensus statement. Nat Rev Gastroenterol Hepatol. 2022 Jan;19(1):60-78.
133. Sridharan K, Sivaramakrishnan G. Disinformation about COVID-19 Preventions and Treatments: Analysis of USFDA Warning Letters. Health Commun. 2021 Sep 20:1-7. doi: 10.1080/10410236.2021.1980254.
132. Sridharan K, Al Jufairi M, Al Ansari E, Jasim A, Eltayab Diab D, Al Marzooq R, Al Madhoob A. Evaluation of urinary acetaminophen metabolites and its association with the genetic polymorphisms of the metabolizing enzymes, and serum acetaminophen concentrations in preterm neonates with patent ductus arteriosus. Xenobiotica. 2021 Sep 16:1-32. doi: 10.1080/00498254.2021.1982070.
131. Sridharan K, Abbasi MY, Mulubwa M. Population Pharmacokinetics and Dose Optimization of Vancomycin in Critically Ill Children. Eur J Drug Metab Pharmacokinet. 2021 Jun 22. doi: 10.1007/s13318-021-00695-z.
130. Sridharan K, Sivaramakrishnan G. Topical corticosteroids for phimosis in children: a network meta-analysis of randomized clinical trials. Pediatr Surg Int. 2021 May 15. doi: 10.1007/s00383-021-04906-1. Epub ahead of print. PMID: 33991205.
129. Sridharan K, Sivaramakrishnan G. Comparative assessment of interventions for treating cutaneous leishmaniasis: A network meta-analysis of randomized clinical trials. Acta Trop. 2021; 220: 105944.
128. Sridharan K, Al Banna R, Husain A. Is there a circannual variation in the anticoagulation control of warfarin? Eur J Hosp Pharm. 2021 Apr 26: ejhpharm-2021-002793. doi: 10.1136/ejhpharm-2021-002793. Epub ahead of print. PMID: 33903173.
127. Al Segai O, Sridharan K, Hammad M, Hammad M. Evaluation of serum vitamin D levels in COVID-19 positive critically ill adults. Pharmacia 2021; 68: 347-350.
126. Stuart B, Maund E, Wilcox C, Sridharan K, Sivaramakrishnan G, Regas C, Newell D, Soulsby I, Tang KF, Finlay AY, Bucher HC, Little P, Layton AM, Santer M. Topical preparations for the treatment of mild to moderate acne vulgaris: systematic review and network meta-analysis. Br J Dermatol. 2021 Apr 7. doi: 10.1111/bjd.20080. Epub ahead of print. PMID: 33825196.
125. Sridharan K, Al Banna R, Malalla Z, Husain A, Sater M, Jassim G, Otoom S. Influence of CYP2C9, VKORC1, and CYP4F2 polymorphisms on the pharmacodynamic parameters of warfarin: a cross-sectional study. Pharmacol Rep. 2021 Apr 3. doi: 10.1007/s43440-021-00256-w. Epub ahead of print. PMID: 33811620.
124. Sridharan K, Sivaramakrishnan G. Interventions for oral lichen planus: A systematic review and network meta-analysis of randomized clinical trials. Aust Dent J. 2021 Mar 8. doi: 10.1111/adj.12835. Epub ahead of print. PMID: 33682925.
123. Sivaramakrishnan G, Alsobaiei M, Sridharan K. Powered toothbrushes for plaque control in fixed orthodontic patients: a network meta-analysis. Aust Dent J. 2021 Mar;66(1):20-31.
122. Sridharan K, Al Jufairi M, Al Ansari E, Al Marzooq R, Hubail Z, Hasan SJR, Al Madhoob A. Intravenous acetaminophen (at 15 mg/kg/dose every 6 hours) in critically ill preterm neonates with patent ductus arteriosus: A prospective study. J Clin Pharm Ther. 2021 Feb 27. doi: 10.1111/jcpt.13384. Epub ahead of print. PMID: 33638909.
121. Sridharan K, Al Jufairi M, Al Ansari E. Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study. Int J Risk Saf Med. 2021 Feb 24. doi: 10.3233/JRS-200058.
120. Farid E, Sridharan K, Alsegai OA, Khawaja SA, Mansoor EJ, Teraifi NA, Qahtani MA, Salman JA. Utility of inflammatory biomarkers in patients with COVID-19 infections: Bahrain experience. Biomark Med. 2021 May 14:10.2217/bmm-2020-0422.
119. Sridharan K, Al Banna R, Husain A. Evaluation of pharmacokinetics of warfarin from validated pharmacokinetic-pharmacodynamic model. ADMET & DMPK 2021; 9: 143-49.
118. Sridharan K, Al Madhoob A, Al Jufairi M, Ansari E, Al Marzooq R. Intravenous frusemide does not interact pharmacodynamically with acetaminophen in critically ill preterm neonates with patent ductus arteriosus. European Review for Medical and Pharmacological Sciences 2021; 25: 1612-1615.
117. Sridharan K, Hasan H, Al Jufairi M, Al Daylami A, Abdul Azeez Pasha S, Al Ansari E. Drug utilisation in adult, paediatric and neonatal intensive care units, with an emphasis on systemic antimicrobials. Anaesthesiol Intensive Ther. 2021 Feb 24:1-7.
2020:
116. Sridharan K, Sivaramakrishnan G. Cerumenolytics with or without manual extraction for impacted earwax: A network meta-analysis of randomised clinical trials. Clin Otolaryngol. 2020 Dec 16. doi: 10.1111/coa.13692.
115. Sridharan K, Sivaramakrishnan G. A network meta-analysis of CYP2C9, CYP2C9 with VKORC1 and CYP2C9 with VKORC1 and CYP4F2 genotype-based warfarin dosing strategies compared to traditional. J Clin Pharm Ther. 2020 Dec 21. doi: 10.1111/jcpt.13334.
114. Hassan ME, Hasan HM, Sridharan K, Elkady A, ElSeirafi MM. Dexamethasone in severe COVID-19 infection: A case series. Respir Med Case Rep. 2020;31:101205.
113. Sridharan K, Banny RA, Husain A. Evaluation of Stable Doses of Warfarin in a Patient Cohort. Drug Res (Stuttg). 2020 Aug 20. doi: 10.1055/a-1228-5033.
112. Sridharan K, Pasha SAA, Qader AM, Hasan HM, ElSeirafi MM. Drug Utilization in Critically ill Adults with Augmented Renal Clearance Compared to Normal Renal Clearance: Implications for use of Antimicrobials with Predominant Renal Excretion. Curr Clin Pharmacol. 2020 Aug 9. doi: 10.2174/1574884715666200810095225.
111. Sridharan K, Al Banna R, Qader AM, Husain A. Does fasting during Ramadan influence the therapeutic effect of warfarin? J Clin Pharm Ther. 2020 Sep 14. doi: 10.1111/jcpt.13254.
110. Sridharan K, Hasan HM, Al Jufairi M, Al Daylami A, Al Ansari E, Qader AM, Pasha SAA. Possible effects of excipients used in the parenteral drugs administered in critically ill adults, children, and neonates. Expert Opin Drug Saf. 2020 Aug 21:1-16.
109. Kashyap R, Murthy S, Arteaga GM, Dong Y, Cooper L, Kovacevic T, Basavaraja C, Ren H, Qiao L, Zhang G, Sridharan K, Jin P, Wang T, Tuibeqa I, Kang A, Ravi MD, Ongun E, Gajic O, Tripathi S; SCCM Discovery CERTAINp Collaborative Investigators. Effectiveness of a Daily Rounding Checklist on Processes of Care and Outcomes in Diverse Pediatric Intensive Care Units Across the World. J Trop Pediatr. 2020 Aug 27:fmaa058. doi: 10.1093/tropej/fmaa058.
108. ElSeirafi MA, Hasan MSNH, Sridharan K, Zamoori A, Alkhawaja S, Azeez Pasha SA. Efficacy and safety of tocilizumab in critically ill adults with COVID-19 infection in Bahrain: A report of 5 cases. Resp. Med. Case Reports 2020; 30: 101139.
107. Sridharan K, Al Banny R, Qader AM, Husain A, Qader KM. Health-related quality of life in patients receiving oral anti-coagulants: a cross-sectional study. Expert Rev Cardiovasc Ther. 2020 May;18(5):309-314.
106. Sridharan K, Al Jufairi M, Qader AM, Elsegai OA. Dose optimization of gentamicin in critically ill neonates. Curr Drug Metab. 2020 May 12. doi: 10.2174/1389200221666200512111131. Epub ahead of print. PMID: 32394828.
105. Al Khaja KAJ, James H, Veeramuthu S, Tayem YI, Sridharan K, Sequeira RP. Prevalence of drugs with constipation-inducing potential and laxatives in community-dwelling older adults in Bahrain: therapeutic implications. Int J Pharm Pract. 2020 May 10. doi: 10.1111/ijpp.12636. Epub ahead of print. PMID: 32390165.
104. Sivaramakrishnan G, Alsobaiei M, Sridharan K. Patient preference and operating time for digital versus conventional impressions: a network meta-analysis. Aust Dent J. 2020 Mar;65(1):58-69.
103. Sridharan K, Al Daylami A. Clinical audit of gentamicin use by Bayesian pharmacokinetic approach in critically ill children. J Infect Chemother. 2020. pii: S1341-321X(20)30021-0.
102. Daylami AA, Sridharan K, Qader A M. Vancomycin nomograms in children admitted to an intensive care unit. Drugs Ther Perspect 2020; 36: 166–172.
101. Sridharan K, Daylami AA, Ajjawi R, Ajooz HAMA. Drug-Induced Liver Injury in Critically Ill Children Taking Antiepileptic Drugs: A Retrospective Study. Curr Ther Res Clin Exp. 2020;92:100580.
2019:
100. Fejzo MS, Trovik J, Grooten IJ, Sridharan K, Roseboom TJ, Vikanes Å, Painter RC, Mullin PM. Nausea and vomiting of pregnancy and hyperemesis gravidarum. Nat Rev Dis Primers. 2019 Sep 12;5(1):62.
99. Sridharan K, Al Daylami A, Ajjawi R, Al-Ajooz H, Veeramuthu S. Clinical pharmacokinetics of Vancomycin in Critically Ill Children. Eur J Drug Metab Pharmacokinet. 2019 Jul 12. doi: 10.1007/s13318-019-00568-6.
98. Sridharan K, Sivaramakrishnan G. Drugs for preventing post-operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: Network meta-analysis of randomized clinical trials and trial sequential analysis. Int J Surg. 2019 Sep;69:1-12.
97. Sridharan K, Al-Daylami A, Ajjawi R, Ajooz HAA. Vancomycin Use in a Paediatric Intensive Care Unit of a Tertiary Care Hospital. Paediatr Drugs. 2019 Jun 20. doi: 10.1007/s40272-019-00343-9.
96. Sridharan K, Sivaramakrishnan G, Kanters S. Adverse pregnancy outcomes between the anti-malarial drugs: Is there a difference between the drugs recommended by World Health Organization? Results of a mixed treatment comparison analysis of randomized clinical trials and cohort studies. Int J Risk Saf Med. 2019 Jan 28. doi: 10.3233/JRS-180022.
95. Sridharan K, Reddy SCK, Mallayasamy S, Chaturvedula A, Kadam P, Hase N, Shukla A, Gogtay N, Thatte U. Population pharmacokinetics of primaquine and the effect of hepatic and renal dysfunction: An exploratory approach. Ind. J Pharmacol 2019;51:17-24.
94. Sridharan K, Sivaramakrishnan G. Vasoactive agents for the management of variceal bleeding: A mixed treatment comparison network meta-analysis and trial sequential analysis of randomized clinical trials. Drug Res (Stuttg). 2019 Feb 18. doi: 10.1055/a-0846-3071.
93. Sridharan K, Sivaramakrishnan G. Comparison of efficacy of remifentanil, sufentanil and alfentanil with fentanyl when combined with propofol for general anesthesia: A systematic review and meta-analysis of randomized controlled trials. Curr Clin Pharmacol. 2019 Mar 13. doi: 10.2174/1567201816666190313160438.
92. Sivaramakrishnan G, Sridharan K. Fluoride varnish versus glutaraldehyde for hypersensitive teeth: a randomized controlled trial, meta-analysis and trial sequential analysis. Clin Oral Investig. 2019;23:209-20.
2018:
91. Sridharan K, Sivaramakrishnan G. Interventions for treating nausea and vomiting in pregnancy: A network meta-analysis and trial sequential analysis of randomized clinical trials. Expert Rev Clin Pharmacol 2018;11:1143-50.
90. Mali NB, Deshpande SP, Karnik ND, Gogtay NJ, Munshi RP, Divatia JV, Wagle SC, Sridharan K, Thatte UM. A multicentric, prospective, observational antibacterial utilization study in Indian tertiary referral centers. Indian J Crit Care Med. 2018;22:723-29.
89. Sridharan K, Sivaramakrishnan G, Sequeira RP, Elamin A. Pharmacological interventions for non-alcoholic fatty liver disease: a systematic review and network meta-analysis. Postgrad Med J. 2018;94:556-65.
88. Sridharan K, Sivaramakrishnan G. Interventions for treating hyperemesis gravidarum: a network meta-analysis of randomized clinical trials. J Matern Fetal Neonatal Med. 2018:1-7. doi: 10.1080/14767058.2018.1519540.
87. Sridharan K, Sivaramakrishnan G. Which antimicrobial agent is likely to be the best for treating Clostridium difficile infections? A Bayesian network meta-analysis of randomized clinical trials. Drug Res (Stuttg). 2018 Sep 7. doi: 10.1055/a-0645-1169.
86. Sridharan K, Sequeira RP. Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. Br J Clin Pharmacol. 2018;84:1906-1916.
85. Sridharan K, Sivaramakrishnan G. Interventions for improving bone mineral density and reducing fracture risk in osteogenesis imperfecta: A mixed treatment comparison network meta-analysis of randomized controlled clinical trials. Curr Clin Pharmacol. 2018;13:190-198.
84. Sridharan K, Sivaramakrishnan G, Sequeira RP, Al-Khaja KA. Pharmacological interventions for premature ejaculation: a mixed-treatment comparison network meta-analysis of randomized clinical trials. Int J Impot Res. 2018;30:215-223.
83. Sivaramakrishnan G, Sridharan K. Role of Serratiopeptidase after surgical removal of impacted molar: A systematic review and meta-analysis. J Maxillofac Oral Surg. 2018;17:122-128.
82. Sridharan K, Sivaramakrishnan G. Efficacy and safety of iron chelators in thalassemia and sickle cell disease: a multiple treatment comparison network meta-analysis and trial sequential analysis. Expert Rev Clin Pharmacol. 2018;11:641-50.
81. Sivaramakrishnan G, Sridharan K. Effect of clonidine on the efficacy of lignocaine local anesthesia in dentistry: A systematic review and meta-analysis of randomized, controlled trials. J Investig Clin Dent. 2018;9:e12296.
80. Sridharan K, Sivaramakrishnan G. Efficacy and safety of alpha blockers in medical expulsive therapy for ureteral stones: a mixed treatment network meta-analysis and trial sequential analysis of randomized controlled clinical trials. Expert Rev Clin Pharmacol. 2018;11:291-307.
79. Sridharan K, Sivaramakrishnan G. Drugs for treating opioid-induced constipation: A mixed treatment comparison network meta-analysis of randomized controlled clinical trials. J Pain Symptom Manage. 2018;55:468-479.
78. Sridharan K, Sivaramakrishnan G. Tranexamic acid in total hip arthroplasty: Mixed treatment comparisons of randomized controlled trials and cohort studies. J Orthop. 2018;15:81-88.
77. Sridharan K, Sivaramakrishnan G. Growth factors for diabetic foot ulcers: mixed treatment comparison analysis of randomized clinical trials. Br J Clin Pharmacol. 2018;84:434-44.
76. Sivaramakrishnan G, Sridharan K. Photodynamic therapy for the treatment of peri-implant diseases: A network meta-analysis of randomized controlled trials. Photodiagnosis Photodyn Ther. 2018;21:1-9.
75. Sridharan K, Sivaramakrishnan G. Prostatectomies for localized prostate cancer: a mixed comparison network and cumulative meta-analysis. J Robot Surg. 2018;12:633-39.
74. Sridharan K, Sivaramakrishnan G. Pharmacological interventions for treating sialorrhea associated with neurological disorders: A mixed treatment network meta-analysis of randomized controlled trials. J Clin Neurosci. 2018;51:12-17.
73. Sridharan K, Sivaramakrishnan G. Pharmacological interventions for preventing acute mountain sickness: a network meta-analysis and trial sequential analysis of randomized clinical trials. Ann Med. 2018;50:147-155.
72. Sridharan K, Sivaramakrishnan G, Gnanaraj J. Pharmacological interventions for stress ulcer prophylaxis in critically ill patients: a mixed treatment comparison network meta-analysis and a recursive cumulative meta-analysis. Expert Opin Pharmacother. 2018;19:151-158.
71. Sivaramakrishnan G, Sridharan K. Oral ketorolac with inferior alveolar nerve block for irreversible pulpitis: A systematic review and meta-analysis. Open Dent J. 2018;12:340-346.
70. Sridharan K, Sivaramakrishnan G. Pharmacological interventions for reducing pain related to immunization or intramuscular injection in children: A mixed treatment comparison network meta-analysis of randomized controlled clinical trials. J Child Health Care. 2018;22:393-405.
69. Sridharan K, Sivaramakrishnan G. Botulinum toxin for refractory trigeminal neuralgia: A trial sequential analysis of randomized clinical trials. J Neurosci Rural Pract. 2018;9:3-4.
68. Sridharan K, Sivaramakrishnan G. Vasoactive agents for hepatorenal syndrome: A mixed treatment comparison network meta-analysis and trial sequential analysis of randomized clinical trials. J Gen Intern Med. 2018;33:97-102.
67. Sridharan K, Sivaramakrishnan G. Tranexamic acid in total knee arthroplasty: Mixed treatment comparisons and recursive cumulative meta-analysis of randomized, controlled trials and cohort studies. Basic Clin Pharmacol Toxicol. 2018;122:111-19.
2017:
66. Sivaramakrishnan G, Sridharan K. Comparison of patient satisfaction with mini-implant versus standard diameter implant overdentures: a systematic review and meta-analysis of randomized controlled trials. Int J Implant Dent. 2017;3:29.
65. Sridharan K, Sivaramakrishnan G. Sublingual immunotherapy in patients with latex allergy: systematic review and meta-analysis of randomized controlled trials. J Dermatolog Treat. 2017;28:600-605.
64. Sivaramakrishnan G, Sridharan K. Electrical nerve stimulation for xerostomia: A meta-analysis of randomised controlled trials. J Tradit Complement Med. 2017;7:409-413.
63. Sridharan K, Sivaramakrishnan G. Medical expulsive therapy in urolithiasis: a mixed treatment comparison network meta-analysis of randomized controlled clinical trials. Expert Opin Pharmacother. 2017;18:1421-31.
62. Sridharan K, Sivaramakrishnan G. Interventions for refractory trigeminal neuralgia: A Bayesian mixed treatment comparison network meta-analysis of randomized controlled clinical trials. Clin Drug Investig. 2017;37:819-31.
61. Sridharan K, Sivaramakrishnan G. Tranexamic acid in total hip arthroplasty: A recursive cumulative meta-analysis of randomized controlled trials and assessment of publication bias. J Orthop. 2017;14:323-28.
60. Sivaramakrishnan G, Sridharan K. Nitrous oxide and midazolam sedation: A systematic review and meta-analysis. Anesth Prog. 2017;64:59-65.
59. Gowri S, Kannan S. Clinical trials in dentistry in India: Analysis from trial registry. Perspect Clin Res. 2017;8:95-99.
58. Sridharan K, Sivaramakrishnan G. Efficacy of topical insulin in wound healing: A preliminary systematic review and meta-analysis of randomized controlled trials. Wound Repair Regen. 2017;25:279-87.
57. Sridharan K, Sivaramakrishnan G. Periodic dosing regimens of atorvastatin and rosuvastatin for dyslipidemia: A systematic review and meta-analysis of randomized controlled trials. Eur J Intern Med. 2017;39:e21-e23.
56. Sridharan K, Sivaramakrishnan G. Literature pollution: a personal experience. Eur J Pediatr. 2017;176:285.
55. Sridharan K, Sivaramakrishnan G. Therapies for meibomian gland dysfunction: A systematic review and meta-analysis of randomized controlled trials. Open Ophthalmol J. 2017;11:346-54.
54. Sivaramakrishnan G, Sridharan K. A systematic review on the effectiveness of titratable over nontitratable mandibular advancement appliances for sleep apnea. J Indian Prosthodont Soc. 2017;17:319-24.
53. Gowri S, Kannan S. Clinical trials in dentistry: Analysis of trial registry. Perspectives in clinical research 2017;8(2):95-99.
2016:
52. Kannan S, Modi T, Bendkhale S, Kulkarni D, Gogtay NJ, Thatte UM. Association of genetic polymorphisms of CYP2C9 and VKORC1 with bleeding due to warfarin. Current Clinical Pharmacology 2016;11:62-8.
51. Swar BD, Bendkhale SR, Rupawala A, Sridharan K, Gogtay NJ, Thatte UM, Kshirsagar NA. Evaluation of cytochrome P450 2C9 activity in normal, healthy, adult Western Indian population by both phenotyping and genotyping. Indian J Pharmacol. 2016;48:248-51.
50. Jha S, Kannan S. Serum prolactin in patients with liver disease in comparison with healthy adults: A cross-sectional study. International journal of applied and basic medical research 2016;6:8-10.
49. Gowri S, Kannan S. Clinical trials in dentistry: Analysis from World Health Organization- International Clinical Trial Registry platform. The journal of evidence-based dental practice 2016; 16:90-5.
48. Gogtay NJ, Kapileshwar S, Shah SU, Bendkhale S, Ramakrishna S, Kannan S, Thelma BK, Thatte UM, Kshirsagar NA. Evaluation of Cytochrome P4502E1 polymorphisms in healthy adult Western Indians and patients with anti-tuberculous drug induced hepatotoxicity. Indian journal of Pharmacology 2016;48:42-6.
47. Kannan S, Mehta M, Gowri S. Awareness and attitude of general public about clinical trials in a developing country. American Journal of Experimental and Clinical Research 2016;3:146-8.
46. Kannan S, Gowri S. Clinical trials in allied medical fields: A cross-sectional analysis of World Health Organization-International Clinical Trial Registry Platform. Journal of Ayurveda and integrated medicine 2016;7:48-52.
45. Gowri S, Kannan S. Adverse drug reactions in the oral cavity. Drugs and Therapy Perspectives 2016; 32:297-303.
44. Patel M, Kannan S, Patel J. Informed consent document and process in India: Ethical and quality issues. Asian Bioethics Review 2016;8:37-52.
43. Swar B, Bendkhale S, Rupawala A, Kannan S, Gogtay NJ, Thatte UM, Kshirsagar NA. Evaluation of CYP2C9 activity in healthy, adult, western Indians by phenotyping and genotyping. Indian Journal of Pharmacology 2016;48:248-51.
42. Kannan S, Gowri S. Health-related research projects in major south Pacific islands: A cross-sectional analysis of Fiji and Papua New Guinea Health Research Portals. International Quarterly of Community Health Education 2016;36:227-30.
41. Kannan S, Malik A, Madan M. Prevalence of methicillin-resistant Staphylococcus aureus colonization in hospital healthcare workers: A cross-sectional study. International Journal of Health and Allied Science 2016;5:169-71.
40. Kannan S, Kataria R, Tolani D, Bendkhale S, Gogtay NJ, Thatte UM. Evaluation of CYP2C19, P2Y12 and ABCB1 polymorphisms and phenotypic response to clopidogrel in healthy Indian adults. Indian Journal of Pharmacology 2016;48:350-4.
39. Gowri S, Kannan S. Local anaesthetic drug administration in dentistry using computer assisted anaesthetic delivery system: A systematic review. The Open Dentistry 2016;10:454-59.
38. Patel M, Kannan S, Patel J. Barrier to ethics committee in India: Ethical and quality issues. Asian Bioethics Review 2016;8:81-93.
37. Sridharan K, Sivaramakrishnan G. Clinical trials in Ayurveda: Analysis of clinical trial registry of India. J Ayurveda Integr Med. 2016;7:141-43.
36. Kannan S, Deshpande S, Sirur S, Gogtay NJ, Thatte UM. Knowledge about clinical trial agreement and clinical trial related insurance amongst ethics committee members: A cross-sectional survey. Perspectives in Clinical Research 2016;7:191.
35. Kannan S, Arora K, Chaudhary S. Off-label drug use in psychiatry: A retrospective audit in a tertiary care hospital. Asian Journal of Psychiatry 2016;24:124.
2015:
34. Kannan S, Khan W, Bhardwaj A, Rathore BS, Khosla PP. Corticosteroid induced cutaneous changes: A cross-sectional study. Indian Journal of Pharmacology 2015;47:696-8.
33. Kannan S, Gowri S, Tyagi V, Kohli S, Jain R, Kapil P, Bhardwaj A. Direct to physician and direct to consumer advertisements: Time to have stringent regulations. International Journal of Risk and Safety in Medicine 2015;27:77-83.
32. Pereira M, Shah N, Desousa A, Bhamrah R, Kannan S. Measuring capacity to consent to research in Indian schizophrenic patients with depressive symptoms. South American Journal of Clinical Research 2015;2:1.
31. Kannan S, Bahl A, Khosla PP. Knowledge and perception of off-label drug use amongst prescribing physicians in a tertiary care hospital. International Journal of Risk and Safety in Medicine 2015;27:219-23.
30. Kannan S, Gowri S. VAS: Verify appropriate statistics. Perspectives in clinical research 2015;6:120.
29. Kannan S, Sharma R, Khosla M, Khosla PP. Economic burden of antimicrobials in a tertiary care hospital. Journal of Research in Medical Education and Ethics 2015;5:32-4.
28. Kannan S, Gowri S. Reporting quality of statistics in Indian journals: Analysis of articles for a period of two years. Journal of Scientometric Research 2015;4:10-3.
27. Gowri S, Shenoy V, Kannan S. Evaluation of effectiveness of intra oral delivery tip on monophase and two-phase impressions- an in vivo study. Journal of oral research and review 2015;7:1-5.
26. Kannan S, Gowri S. Acute porphyria – Drug demon etiology. Drug Development and Therapeutics 2015;6:47-51.
25. Kannan S, Gowri S. Statistics: from arbitrary to accurate reporting is the need of the hour. Journal of Scientometric Research 2015;4:115-8.
24. Kannan S, Gowri S. Audio-visual recording of obtaining informed consent: mandatory for clinical trials. Indian Journal of Dental Research 2015;26:333-5.
23. Bhati N, Kannan S, Khosla PP. Good pharmacovigilance practice: Need of the hour for pharmaceutical companies. Perspectives in clinical research 2015;6:171-2.
22. Aklujkar A, Aklujkar S, Kannan S, Munsi SC, Mehta A. Comparison of Doppler echocardiography and tissue Doppler imaging in the assessment of left ventricular filling pressure. Journal of Clinical and Biomedical Sciences 2015;5:13-6.
21. Kannan S, Gowri S. Pilot studies: Are they treated in an appropriate way? Perspectives in clinical research 2015;6:207-11.
20. Gyanchandani V, Mahatme P, Kannan S, Motwani A. Adherence to preferred reporting items for systematic reviews and meta-analysis protocols guidelines: A cross-sectional analysis from medical databases. South American Journal of Clinical Research 2015;2:1-13.
19. Gowri S, Mehta D, Kannan S. Antibiotic use in dentistry: A cross-sectional survey from a developing country. Journal of Orofacial sciences 2015;7:90-4.
18. Seahloli MS, Kannan S, Demana P. Current status and potential of South African hospitals to implement research to overcome health challenges, archive international health goals and increase capacity of clinicians and nurses. South American Journal of Clinical Research 2015;2:1-7.
2014:
17. Bang V, Mallad A, Kannan S, Bavdekar SB, Gogtay NJ, Thatte UM. Awareness about and views of parents on the off-label drug use in children. International Journal of Risk and Safety in Medicine 2014;26:61-70.
16. Gowri S, Kannan S. Bisphosphonates induced osteonecrosis of jaw: Medical implications and dental complications. Adverse Drug Reaction Bulletin 2014;289:1115-8.
15. Kannan S, Gowri S. A study with spoof paper - reflection of reviewing processes in open - access journals. J Pharmacol Pharmacother. 2014;5:70.
14. Yadav S, Kannan S, Vaideeswar P, Gogtay NJ, Thatte UM. Methotrexate-induced pneumonitis and myocarditis. Indian Journal of Pathology and Microbiology 2014;57:152-3.
13. Kannan S, Gowri S. Contradicting/Negative results inclinical research: Why (do we get these)? Why not (get these published)? Where (to publish)? Perspectives in Clinical Research 2014;5:151-3.
12. Kannan S, Shanti M, Meher Ali. Anxiolytic, sedative and hypnotic activities of aqueous extract of Morinda citrifolia fruit. Journal of Ayurveda and Integrative Medicine 2014;5:73-5.
11. Karnik ND, Kannan S, Tiwari D, Gupta V. CYP2C9*3 polymorphism presenting as lethal subdural hematoma on low-dose warfarin. Indian Journal of Pharmacology 2014;46:549-50.
10. Kannan S, Kadam PP, Gogtay NJ, Thatte UM. Pharmacokinetics of primaquine single dose (15 mg) in patients with chronic kidney disease undergoing hemodialysis. Journal of Association of Physicians of India 2014;62:107-8.
9. Gogtay NJ, Mali NB, Iyer K, Kadam PP, Sridharan K, Shrimal D, Thatte UM. Evaluation of Cytochrome P450 2D6 phenotyping in healthy adult Western Indians. Indian Journal of Pharmacology 2014;46:266-69.
8. Kannan S, Gowri S. Redundant publications: Expect the unexpected. Indian Journal of Pharmacology 2014;46:663-4.
7. Kannan S, Gowri S. Anti-plagiarism software: What they can and cannot do. Journal of Scientometric Research 2014;3:93-4.
6. Kannan S, Gowri S. Motivating factors for recruitment of children in clinical trials. International Journal of Biological and Medical Research 2014;5:4518-20.
5. Karnik ND, Kannan S, Gupta V. Candidal septicaemia following intravenous immunoglobulin. South American Journal of Medicine 2014;2:1-4.
2013:
4. Kulkarni SP, Shah SR, Kadam PP, Kannan S, Hase NK, Shetty PP, Thatte UM, Gogtay NJ. Pharmacokinetics of primaquine single dose (15 mg) in patients with chronic kidney disease. Indian Journal of Pharmacology 2013;45:330-3.
3. Kannan S, Deshpande SP, Gogtay NJ, Thatte UM. Policy of reviewing statistics in Indian medical and surgical journals. Journal of Pharmacology and Pharmacotherapeutics 2013;4:139-40.
2012:
2. Thatte UM, Gogtay NJ, Kannan S, Oak SN. Access to medicines for orphan disease-experiences in the management of a case of Fasciola hepatica in Mumbai, India. Nat Med Jr Ind 2012;25:234-35.
2011:
1. Gogtay NJ, Doshi BM, Kannan S, Thatte UM. A study of warning letters issued to clinical investigators and institutional review boards by the United States food and drug administration. Ind Jr Med Ethics 2011;8:211-14.
Grants,Awards and Certifications
Grants :
1. “Association of genetic polymorphisms of CYP2C9 and VKORC1 with adverse effects of warfarin” - from Department of Biotechnology, Government of India – USD 44000 – Project completed, and the manuscript has been published.
2. Genetic polymorphisms of CYP2C19, ABCB1 and P2Y12 with response to clopidogrel in normal healthy participants – from Indian Council of Medical Research, Government of India – USD 43000 – Project completed, and manuscript has been published.
3. Granted Travel support from Department of Biotechnology, Government of India for presenting a paper entitled, “SNPs of CYP2C19, ABCB1, P2Y12 and response to clopidogrel” in First international congress on Personalized Medicine at Florence, Italy.
4. Granted International Meeting travel grant support from International Society of Pharmacoeconomics and Outcomes Research (ISPOR) to attend 19th Annual European Congress held in Vienna, Austria between 29 Oct 2016 and 02 Nov 2016.
5. Granted USD 4000 for a project entitled, “A randomized clinical trial comparing fluoride varnish versus glutaraldehyde for hypersensitive teeth” from Fiji National University in 2015. The study was completed and published in Clinical Oral Investigations.
6. Granted Congress bursary from the Organizing Committee of 18th World Congress of Basic and Clinical Pharmacology (WCP 2018) for presenting a poster entitled, “Pharmacological interventions for treating premature ejaculation: A mixed treatment comparison network meta-analysis of randomized clinical trials” held in Kyoto, Japan between 01 and 07 June 2018.
7. Sanctioned an intramural grant in Arabian Gulf University for around USD 22000 for a project (as principal investigator) entitled, “Association between pharmacokinetics and pharmacogenetics with the clinical efficacy and safety of intravenous acetaminophen in pre-term neonates with patent ductus arteriosus” in December 2018. The study is completed, and 2 manuscripts published (each in Journal of Clinical Pharmacy and Therapeutics and European Review for Pharmacological and Medical Sciences), and 2 are in journal’s consideration for publication.
8. Granted USD 18000 through AGU-RCSI joint research funding for carrying out a clinical research (as principal investigator) entitled, “Association of CYP2C9, VKORC1 and CYP4F2 in patients on warfarin: A cross-sectional study” during April 2019. The study is completed, and four manuscripts published each in Pharmacological Reports, European Journal of Hospital Pharmacy, Expert Review of Cardiovascular Pharmacology, and ADMET and DMPK.
9. Sanctioned an intramural grant in Arabian Gulf University for around USD 1000 for a project (as principal investigator) entitled, “Validating PACT questionnaire in patients receiving warfarin in a tertiary care hospital” in December 2018. The study was completed and published in Expert Review of Cardiovascular Therapy.
10. UK National Institute for Health Research School for Primary Care Research (NIHR SPCR; Grant number: 442) for network meta-analysis of topical treatments for acne vulgaris in July 2019. The study is completed, and the manuscript is published in British Journal of Dermatology.
11. Obtained an intramural grant of 35500 USD for the project (as principal investigator) entitled, “Urinary biomarkers in early identification of drug-induced nephrotoxicity in critically ill neonates”. The study is completed, and the manuscript is published.
12. Granted 26500 USD from AGU-RCSI joint research funding for the project (as principal investigator) entitled, “Oxidative stress markers and single nucleotide polymorphisms of the antioxidant enzymes in preterm neonates with respiratory distress syndrome receiving external surfactant compared to controls” in June 2021. The recruitment is completed and data analysis is ongoing.
Awards & Prizes :
1. Under-graduation (MBBS) - Distinction (76%) in the subject of Pharmacology.
2. First prize for the presentation entitled, “Recent trends in the management of leprosy” in a Symposium on leprosy for post graduate medical students by conducted by Damien Foundation India Trust held on September 13, 2006 in Madurai Medical College, India.
3. Best paper presentation for the study entitled, “Comparative study on efficacy and adverse effects of Haloperidol and Risperidone in first episode psychosis patients” in 39th Annual conference of Indian Pharmacological Society held at Jaipur, India in December 2006.
4. Best paper presentation entitled, “Anxiolytic, sedative and hypnotic activities of aqueous extract of Morinda citrifolia fruit in mice” in Southern Regional Indian Pharmacological Society held at JIPMER, Puducherry, India in July 2008.
5. First prize in National level Pharmacology quiz – 2008 “International conference on Translational pharmacology and 41st Annual conference of Indian Pharmacological Society” held at AIIMS, New Delhi, India.
6. Dr.UK Sheth prize for the paper presentation entitled, “A study of Warning Letters issued to clinical investigators and institutional review boards by the United states food and drug administration” in the third International Conference of South Asian Chapter of American College of Clinical Pharmacology held at Mumbai, India from 2nd to 4th October 2009.
7. First prize for the paper presentation entitled, “Pharmacokinetics of single dose (15 mg) of primaquine in special population and normal volunteers” at the Scientific meeting of Staff Society in Seth GS Medical College & KEM Hospital, Mumbai, India held on 24th February 2011.
8. Dr.GB Parulkar prize for the paper presentation entitled, “Demographics of animal bite victims in a tertiary care hospital in Mumbai” in South Asian Chapter of American College of Clinical Pharmacology- 5th International Annual Conference “Clinical Pharmacology-Discovery, Development and beyond” held on 27th and 28th Aug 2011.
9. Prof. Manjeet Singh prize for the best paper in molecular biology entitled, “Association of genetic polymorphisms of CYP2C9 and VKORC1 with adverse effects due to warfarin” at the 44th National conference of Indian Pharmacological Society, Manipal, India during Dec 2011.
10. First prize for the paper presentation entitled, “Association of genetic polymorphisms of CYP2C19, ABCB1, P2Y12, Prakriti and response to clopidogrel in healthy normal volunteers” at the Scientific meeting of Staff Society in Seth GS Medical College & KEM Hospital, Mumbai, India held during February 2012.
11. Second prize for the paper presentation entitled, “Awareness of off-label drug use in children amongst the general public” in the Second national conference of Forum for Ethics Review Committee in India during July 2013 in PSG Institute of Medical Sciences and Research, Coimbatore, India.
