Joseph Cotten

Faculty, Massachusetts General Hospital 

Location: United States

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Dr.Cotten's research focuses on the molecular mechanism by which volatile anesthetics potentiate TASK tandem pore potassium channel function and the role of these pH- and hypoxia-sensitive channels in regulation of breathing. We use an Ussing chamber electrophysiologic system to study these channels and employ a number of molecular techniques, including molecular co-expression, site-directed mutagenesis, and RNA interference. 


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