Jairo Diaz
PATHOLOGIST, hospital departamental de villavicencio
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We have been working in cancer for more than 12 years when we published our first article in PLOSone. Documenting geometric structures with a chiral component, later we verified that this geometry was a formative precursor in the assembly of perfect structures that mimic embryoid bodies and that appear in the vast majority of malignant tumors that I invite you to refer to see them in our referenced publications later. Today we know why these structures are formed and their meaning: ESTs embryoid structures are formed by an emergent activation of genes that process embryogenesis, tumor cells undergo structural metamorphosis which is mediated by the appearance of chiral components in the microenvironment that we identify as chiral complexes incorporating laterality and polarity into the cellular microenvironment that It is the morphological template for the cells to take a cephalo-caudal polar position, as you can see in the images documented by us. ONCE THE TUMOR CELLS UNDERGO MEDIUM METAMORPHOSIS, on the one hand, due to the activation of genes that come from emvriogenesis, as well as from the appearance of chiral components, they acquire a phenotype EMBRYOF LIKE, THIS NEW PHENOTYPE ACQUIRED BY MALIGNANT CELLS HAS A PURPOSE It allows tumor cells to re-enter the cell cycle and be regulated again by the cell death apoptosis system of programmed cell death,,, this process determines which cells immortal tumors become mortal within the tumor
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Publications
1) Cell Tissue Kinet 1988 Jul;21(4):213-9. doi: 10.1111/j.1365-2184.1988.tb00780.x.
Effect of chemical ablation of myenteric neurones on intestinal cell proliferation
S Zucoloto 1, J A Diaz, J S Oliveira, G Muccilo, V N Sales Neto, J K Kajiwara cias
2) Nutrition Researc hVolume 15, Issue 8, August 1995, Pages 1173-1180
Relationship of a fiber-rich diet and epithelial cell proliferation in the denervated distal colon in the rat Author links open overlay panelMaria Inez MFernandesMD, P
#Jairo DiazTorresMD+GersonMuccilloPhD†Antonio CarlosIglesiasMD, MSc∗SergioZucolotoMD, PhD
3) Geometric Triangular Chiral Hexagon Crystal-Like Complexes Organization in Pathological Tissues Biological Collision Order
Jairo A. Díaz ,Natalia A. Jaramillo,Mauricio F. Murillo
Published: December 12, 2007 https://doi.org/10.1371/journal.pone.0001282
4) Framework of Collagen Type I – Vasoactive Vessels Structuring Invariant Geometric Attractor in Cancer Tissues: Insight into Biological Magnetic Field
Jairo A. Díaz ,Mauricio F. Murillo,Natalia A. Jaramillo
Published: February 18, 2009
https://doi.org/10.1371/journal.pone.0004506
https://doi.org/10.2147/CMAR.S25810
5) Diaz, J. A., & Murillo, M. F. (2012). Phenotype characterization of embryoid body structures generated by a crystal comet effect tail in an intercellular cancer collision scenario. Cancer management and research, 4, 9–21. https://doi.org/10.2147/CMAR.S25810
6)) Cancer Manag Res 2011;3:143-55. doi: 10.2147/CMR.S17402. Epub 2011 May 11.
Intercellular cancer collisions generate an ejected crystal comet tail effect with fractal interface embryoid body reassembly transformation Jairo A Díaz 1, Mauricio F Murillo, Alvaro Barrero
7) Article published in GEOLOGY journal
Open Journal of Geology Vol.3 No.3，July 4, 2013
Electromagnetic Field Released in Collision-Impact Events Generate in the Matrix Interface Fractal Scalable Invariant Geometric Triangular Chiral Hexagonal Structures
Jairo A. Diaz
DOI: 10.4236/ojg.2013.33022
8) Article published in ASTROPHYSICS JPOURNAL journal
Jairo A. Diaz, Karen E. Paris
International Journal of Astronomy and Astrophysics Vol.4 No.1，March 28, 2014
DOI: 10.4236/ijaa.2014.41025 5.745 Downloads 8.582 Views
Identification of Mosaic Order Area of Geometric Triangular Chiral Hexagonal Complexes in Interphase with Morphology Biosignature Pattern in the Interior of Martian Nested Impact Craters
9) Geometric triangular chiral hexagon complexes and clonal embryogenic body organization on the Turin Shroud crucified man image: A predictable tissue response to injury
Jairo A. Diaz
DOI: 10.4236/ns.2013.510135 Natural Science Vol.5 No.10，October 10, 2013
10) Am J Stem Cells 2016 Aug 20;5(2):53-73. eCollection 2016.
Human somatic cells acquire the plasticity to generate embryoid-like metamorphosis via the actin cytoskeleton in injured tissues
Jairo A Diaz 1, Mauricio F Murillo 2, Jhonan A Mendoza 3, Ana M Barreto 3, Lina S Poveda 3, Lina K Sanchez 3, Laura C Poveda 3, Katherine T Mora 3
11) Sequential development of embryoblast-like memory entities in human cancer tissues: An evolutionary self-repair structure with pluripotentiality
Jairo A Diaz, Liliana Sánchez, Luis A Diaz, Mauricio F Murillo, Laura Poveda, Oscar F Suescun, Laura Castro doi: https://doi.org/10.1101/2020.10.02.324376
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