LIST OF PUBLICATIONS 

1. IV Onyishi, SA Chime, AA Attama: Evaluation of excipient potentials of Irvingia wombolu fats and Moringa oil in rifampicin-loaded lipospheres: in vitro-in vivo characterization J. Drug Del. Sci. Tech 24 (4) (2014) 404-412

1. EE Chinaeke, SA Chime, IV Onyishi, AA Attama, VC. Okore: Formulation development and evaluation of the anti-malaria properties of sustained release artesunate-loaded solid lipid microparticles based on phytolipids. Drug Delivery Early Online 1-14 (2014)

1. IV Onyishi, SA. Chime, EO Ogudiegwu: Formulation of novel sustained release rifampicin-loaded solid lipid microparticles based on structured lipid matrices from Moringa oleifera. Pharmaceutical Development and Technology. Early Online 1-9 (2014)

1. SA Chime, IV Onyishi, GC Onunkwo, AA Attama: Solidified reverse micellar solution (SRMS)-based indomethacin sustained-release tablets: Formulation and in vitro evaluation. Trop J Pharm Res, 13(2): 211-216 (2014)

1. IV Onyishi, SA. Chime, I Kanu: Application of Ipomoea batatas starch as suspending agent in acetaminophen suspension. Afr. J. Pharm. & Pharmacology. 8(1) 24-30 (2014)

1. SA Chime, IV Onyishi, PU Ugwoke, AA Attama: Evaluation of the properties of Gongronema latifolium in Phospholipon 90H-based solid lipid microparticles (SLMs): An antidiabetic study. Journal of Dietary Supplements, 11 (1) 7-18 (2014)

1. SA Chime, EC Umeyor, IV Onyishi, GC Onunkwo, AA Attama. Analgesic and micromeritic evaluations of solidified reverse micellar solution (SRMS)‑based oral lipospheres of diclofenac potassium.  Indian J Pharm Sci.75(3):302-309(2013)

1. SA Chime, IV Onyishi, MA Momoh, AA Attama Anti-inflammatory, antinociceptive and ulcerogenic properties of indomethacin tablets based on solidified reverse micellar solution (SRMS).  Afr. J. Pharm. & Pharmacology. 7(43) 2813-2822 (2013)

1. IV Onyishi, SA. Chime, E Egwu: Application of ĸ-carrageenan as a sustained release matrix in floating tablets containing sodium salicylate. Afr. J. Pharm. & Pharmacology. 7(39), 2667-2673, (2013)

1. SA Chime, IV Onyishi, CA Ugwu: Artemether-lumefantrine-loaded lipospheres: evaluation of properties of Solutol® hs 15 and Soluplus® on the in vitro properties. Innovare Journal of Sciences,  1 (3) 4-9(2013)

1. SA Chime, IV Onyishi: Solidified reverse micellar solutions (SRMS): A novel approach for controlling drug release from various lipids based drug delivery systems. Afr. J. Biotechnology 12 (52), 7138-7146, (2013)

1. IV Onyishi, SA. Chime: Comparative functionality evaluation of co-precipitate of Zea mays and Oryza sativum starch in paracetamol tablets. Int. J. Pharm. Sci. Rev. Res., 22(2), 18-22 (2013)

1. SA Chime, IV Onyishi JO Onyechi: Co-processed metronidazole granules for tabletting: Formulation and in vitro evaluation. Int. J. Pharm. Sci. Rev. Res., 22(2), 13-17 (2013)

1. SA Chime, NC Obitte,  IV Onyishi, IE Nwosu: Development of cross-linked alginate beads by ionotropic gelation technique for controlled release of diclofenac sodium Am. J. Pharm Tech Res. 3(5) 427-437 (2013).

1. SA Chime, IV Onyishi, SA Brown, AA Attama, EC Idogwu, GC Onunkwo: Diclofenac potassium–loaded dika fat solid lipid microparticles: In vitro and in vivo characterisation. BioMedRx 1(3), 227-234 (2013)

1. IV Onyishi, SA. Chime, C Okeke: Evaluation of the antioxidant properties of Vitis vinifera juice extract in rifampicin dispersions .Afr. J. Pharm. & Pharmacology. 7(24), 1619-1624, (2013)

1. JO Onyechi, SA Chime, IV Onyishi, SA Brown, PO Eleigwe, GC Onunkwo:  Formulation and evaluation of Allium sativum tablets for improved oral delivery. Int. J. Pharm. Sci. Rev. Res., 22(2), 6-10 (2013).

1. SA Chime, EC Ugwoke, IV Onyishi, SA Brown, GC Onunkwo: Formulation and evaluation of Alstonia boonei stem bark powder tablets. Indian J Pharm Sci. 75(2):221-226(2013).

1. SA Chime, IV Onyishi, MA Momoh, GC Onunkwo: Formulation and evaluation of ethanolic extract of Crytolepis sanguinolenta root tablets. Innovare Journal of Sciences,  2 (3)10-13(2013).

1. JO Onyechi, SA Chime, IV Onyishi, A Eneiga: Formulation of Dennettia tripetala tablets by direct compression: Standardization and quality control. Int. J. Pharm. Sci. Rev. Res., 22(2), 1-4 (2013).

1. IV Onyishi, SA. Chime, CV Adibe: Formulation of pyridoxine hydrochloride sustained release capsules: Effect of propylene glycol co-solvent on the in vitro release. Afr. J. Pharm. & Pharmacology. 7(15), 809-815, (2013).

1. SA Chime, IV Onyishi, GC Onunkwo: In vitro properties of solid lipid microparticles (SLM) loaded with methanolic extract of Garcinia kola (Heckel) seed. Innovare Journal of Ayurvedic Sciences. 1(1) 1-5 (2013).

1. SA Chime, GC Onunkwo, IV Onyishi: Kinetics and mechanisms of drug release from swellable and non-swellable matrices: A review.  Research Journal of Pharmaceutical, Biological and Chemical Sciences. 4(2) 97-103 (2013).

1. SA Chime, IV Onyishi: Lipid-based drug delivery systems (LDDS): Recent advances and applications of lipids in drug delivery. Afr. J. Pharm. & Pharmacology.  7(48), 3034-3059, (2013)

1. SA Chime, IV Onyishi, AA Attama, GC Onunkwo, MC Ajaraonye: Lipospheres: A potential delivery system of herbal extract for the treatment of diabetes mellitus. Am. J. PharmTech Res. 3(4) 480-491 (2013).

1. IV Onyishi, SA. Chime, JC Ugwu: Evaluation of binder and disintegrant properties of starch derived from Xanthosoma sagittifolium in metronidazole tablets. Afr. J. Biotechnology.  12(20), 3064-3070, (2013)

1. IV Onyishi, SA. Chime: Physicochemical characterisation of Irvingia wombolu gum in tramadol encapsulated granules. Afr. J. Pharm. & Pharmacology.  7(42), 2788-2793, (2013).

1. SA Chime, IV Onyishi, AA Attama, GC Onunkwo: Preliminary investigation of the properties of diclofenac potassium in SRMS-based tablets. Afr. J. Pharmaceutical Res. Dev. 5(1) 17-24 (2013).

1. IV Onyishi, SA. Chime, CA Okoroji: Physicochemical properties of microcrystalline cellulose from Saccharum officinarum: Comparative evaluation with Avicel® pH 101. Am. J. PharmTech Res. 3(5) 414-426 (2013).

1. SA Chime, IV Onyishi, NC Obitte, GC Onunkwo, GI Odo: Sustained release artemether-loaded solid microparticles, based on solidified reverse micellar solution (SRMS). Innovare Journal of Sciences, 1 (2)1-7(2013)

1. SA Chime, CE Ugwoke, IV Onyishi, SA Brown, CE Ugwu, GC Onunkwo: Formulation and evaluation of Cymbopogon citrates dried leaf-powder tablets. .Afr. J. Pharm. & Pharmacology 6(48),  3274-3279  (2012)

1. IV Onyishi, SA. Chime, GA Ugwoke: Formulation and evaluation of Mucuna pruriens based acetaminophen suspension. Journal of Pharmacy Research 5(9), 4821-4823 (2012).

1. IV Onyishi, SA. Chime, FC Odika, NC Obitte: Formulation development and comparative evaluation of acetaminophen suspension using polysaccharide derived from seed cotyledons of Irvinga wombolu. Int. J. Pharm. Sci. Rev. Res., 17(1), 11-15 (2012).

1. MA, Momoh, SA Chime, IV Onyishi, Natural healing compound for the treatment of excision and incision wound in rats model. Int. J. Pharm. Sci. Rev. Res., 17(1), 1-5 (2012).

1. NC Obitte, SA Chime,AA Margret,  AA Attama, IV Onyishi,  SA Brown: Some in vitro and pharmacodynamic evaluation of indomethacin solid lipid microparticles. Afr. J. Pharm. & Pharmacology.  6(30), 2309-2317, (2012)

1. NC Obitte, A Chukwu, IV Onyishi, BCN Obitte: The Physicochemical evaluation and applicability of Landolphia owariensis latex as a release modulating agent in its admixture with Carbosil® in ibuprofen-loaded self-emulsifying oil formulations. International Journal of Applied Research in Natural Products .2(4) 27-43 (2010).

1. NC Obitte, A Chukwu, IV Onyishi: The use of a pH-dependent and non-pH-dependent natural hydrophobic biopolymer (Landolphia owariensis latex) as capsule coating agents in in vitro controlled release of metronidazole for possible colon targeted delivery. International Journal of Applied Research in Natural Products 3(1) 1-17 (2010).

1. EC Ibezim,  PR Duchowicz, NE Ibezim, LMA Mullen, IV Onyishi, SA Brown, EA Castro. Computer-aided linear modelling employing QSAR for drug discovery. Scientific Research and Essay 4(13), 1559-1564, (2009).

1. EC Ibezim, AA Attama, NC Obitte, IV Onyishi, SA Brown: In vitro prediction of in vivo bioavailability and bioequivalence of brands of metronidazole tablets in Eastern Nigerian drug market. Scientific Research and Essay 3(11), 552-558, (2008).

1. NC Obitte, H Ezeiruka, IV Onyishi: Preliminary Studies of two vegetable oil-based self emulsifying drug delivery system (SEDDS) for the delivery of metronidazole, a poorly water soluble drug. Journal of Applied Sciences 8(10) 1950-1955 (2008).

1. EC Ibezim, SI Ofoefule, EO Omeje, IV Onyishi, UE Odo: The role of ginger starch as a binder in acetaminophen tablets. Scientific Research and Essay 3(2), 046-050, (2008).

1. EC Ibezim, CO Esimone, O Okorie, IV Onyishi, PO Nnamani, SA Brown, CE Obodo:  A study of the in vitro interaction of cotrimoxazole and ampicillin using the checkerboard method. Afr. J. Biotechnology 5 (13), 1284-1288, (2006)

1. EC Ibezim, CO Esimone, PO Nnamani, IV Onyishi, SA Brown, CE Obodo:  In vitro study of the interaction between some fluoroquinolones and extracts of kola nitida seed. Afr. J. Biotechnology 5 (19), 1781-1784, (2006)