Damalie Nakanjako
Prof, Makerere University
Location:
Consulting Services
Areas Of Interest
Professional Narrative
I am a Professor of Medicine, and Principal of the College of Health Sciences, Kampala, Uganda, and immediate past Dean of the School of Medicine. I have over 22 years' experience in HIV/AIDS care at different platforms including community trials with simple interventions such as safe water and cotrimoxazole prophylaxis to reduce morbidity and mortality among people living with HIV, hospital-based studies on basic tools like provider-initiated HIV testing and routine TB screening to improve access to HIV diagnosis, management of TB-HIV co-infections and timely initiation of anti-retroviral therapy in a hospital setting, epidemiological studies to understand immune recovery in long-term HIV treatment cohorts, laboratory-based studies to understand cellular mechanisms of suboptimal immune recovery, as well as clinical trials on innovative interventions of adjuvant therapy to maximize the benefits of antiretroviral therapy. I have been involved in evaluation of health systems and national policy review processes to inform national HIV/AIDS care policies. I have written a book entitled, "Efficient HIV/AIDS care in resource-limited settings" (ISBN 978-3-639-33430-2), a book chapter in the Springer book, "Women, Motherhood and Living with HIV/AIDS', A Cross-Cultural Perspective (ISBN 978-94-007-5886-5 and several publications in international peer-reviewed journals. In recognition of the contribution my work on optimizing HIV treatment outcomes and reducing HIV-associated morbidity and mortality in sub-Saharan Africa, I won the 2013 Merle A. Sande Health Leadership Award.
I have mentored over 50 trainees including local and international masters’ level, doctoral and post-doctoral research fellows as well as junior and mid-level faculty members. I was a working group member of the Afya bora Consortium for global health leadership training in Africa, and a mentor on the NIH-funded “Nurture” research training and mentoring program for career development of faculty at Makerere University. I am a member of the steering committee of the GloCal Consortium NIH Global Health Program for fellows and scholars at UCSF and the Research Enterprise to Advance a Cure for HIV (REACH) Collaboratory at Well Cornell Medicine and Training Advisory Committee on Uganda Cancer institute-Fred Hutch D43 program.
Employment
Education
Referees
Harriet Mayanja, Makerere University.
“Professor”
Alison Elliot, London School of Hygiene and Tropical Medicine.
“Professor”
Publications
Farrant MT, Masyuko SJ, Kinuthia J, Osoti AO, Mogaka JN, Temu TM, Zifodya JS, Nakanjako D, Ameda F, Farquhar C, Page ST. Association of HIV, cardiovascular risk factors, and carotid intimal media thickness: A cross-sectional study in Western Kenya. Medicine (Baltimore). 2022 Nov 25;101(47):e31366. doi: 10.1097/MD.0000000000031366. PubMed PMID: 36451447; PubMed Central PMCID: PMC9704953.
Nanyeenya N, Kiwanuka N, Nakanjako D, Nakigozi G, Kibira SPS, Nabadda S, Kiyaga C, Sewanyana I, Nasuuna E, Makumbi F. Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa. Afr J Lab Med. 2022;11(1):1899. doi: 10.4102/ajlm.v11i1.1899. eCollection 2022. Review. PubMed PMID: 36353193; PubMed Central PMCID: PMC9639359.
Kalanzi D, Mayanja-Kizza H, Nakanjako D, Semitala F, Mboowa G, Mbabali M, Kigozi E, Katabazi FA, Sserwadda I, Kateete DP, Achan B, Sewankambo NK, Muwonge A. Microbial characteristics of dental caries in HIV positive individuals. Front Oral Health. 2022;3:1004930. doi: 10.3389/froh.2022.1004930. eCollection 2022. PubMed PMID: 36211252; PubMed Central PMCID: PMC9533146.
Otiti-Sengeri J, Omaido BA, Bhwana D, Nakanjako D, Missiru M, Muwonge M, Amaral LJ, Mmbando BP, Colebunders R. High Prevalence of Glaucoma among Patients in an Onchocerciasis Endemic Area (Mahenge, Tanzania). Pathogens. 2022 Sep 14;11(9). doi: 10.3390/pathogens11091046. PubMed PMID: 36145478; PubMed Central PMCID: PMC9501165.
Yusuf AM, Lusobya RC, Mukisa J, Batte C, Nakanjako D, Juliet-Sengeri O. Validity of smartphone-based retinal photography (PEEK-retina) compared to the standard ophthalmic fundus camera in diagnosing diabetic retinopathy in Uganda: A cross-sectional study. PLoS One. 2022;17(9):e0273633. doi: 10.1371/journal.pone.0273633. eCollection 2022. PubMed PMID: 36067194; PubMed Central PMCID: PMC9447889.
Nakanjako D, Omaswa F. Editorial: A century of health professions' education, training, academic research and service at Makerere University, Kampala, Uganda. Afr Health Sci. 2022 Aug;22(Spec Issue):iii-vii. doi: 10.4314/ahs.v22i2.2S. PubMed PMID: 36321129; PubMed Central PMCID: PMC9590323.
Mulinde B, Atukunda I, Kawooya I, Sebabi FO, Mukunya D, Batte C, Nakanjako D, Nakiyingi L, Nalukenge C, Nakubulwa F, Musiika AA, Otiti-Sengeri J. Prevalence and risk factors for visual impairment among elderly patients attending the eye clinic at Mulago National Referral Hospital, Uganda: a cross-sectional study. Afr Health Sci. 2022 Aug;22(Spec Issue):124-132. doi: 10.4314/ahs.v22i2.18S. PubMed PMID: 36321128; PubMed Central PMCID: PMC9590326.
Nakanjako D, Castelnuovo B, Sewankambo N, Kakaire T, Brough RL, Katabira ET, Thomas DL, Quinn TC, Colebunders R, Greene WC, Ronald AR, Coutinho A, McAdam K, Serwadda D, Wabwire-Mangen F, Katongole-Mbidde E, Musoke P, Joloba M, McKinnell H, Kamya M, Mayanja-Kizza H, Manabe YC, Kambugu A. Infectious Diseases Institute at Makerere University College of Health Sciences: a case study of a sustainable capacity building model for health care, research and training. Afr Health Sci. 2022 Aug;22(Spec Issue):1-10. doi: 10.4314/ahs.v22i2.3S. PubMed PMID: 36321127; PubMed Central PMCID: PMC9590334.
Nakanjako D, Byamugisha J. Health Service delivery and training at Makerere University College of Health Sciences: The role of the academic health centers' network. Afr Health Sci. 2022 Aug;22(Spec Issue):63-67. doi: 10.4314/ahs.v22i2.10S. PubMed PMID: 36321126; PubMed Central PMCID: PMC9590325.
Okello E, Ssemogerere L, Ssinabulya I, Kayima J, Nakanjako D, Sebatta E, Lubega S, Oketcho M, Mwambu T, Lwabi P, Mijumbi C, Omagino J. Makerere University-Uganda Heart Institute collaborative cardiovascular disease training and research since 1988. Afr Health Sci. 2022 Aug;22(Spec Issue):68-70. doi: 10.4314/ahs.v22i2.11S. PubMed PMID: 36321124; PubMed Central PMCID: PMC9590329.
Nakanjako D, Mayanja EK, Rwashana AS, Semitala F, Katureebe C, Ssali M, Muddu M, Ssinabulya I. Mobile Phone-based Intervention to promote un-interrupted HIV treatment during the COVID-19 pandemic. Afr Health Sci. 2022 Aug;22(Spec Issue):85-92. doi: 10.4314/ahs.v22i2.14S. PubMed PMID: 36321123; PubMed Central PMCID: PMC9590328.
Nakanjako D, Bamuturaki G, Nambooze H, Sewankambo N. Use of individual development plans: experiences from junior faculty in the "NURTURE" mentored research program at Makerere University College of Health Sciences. Afr Health Sci. 2022 Aug;22(Spec Issue):71-79. doi: 10.4314/ahs.v22i2.12S. PubMed PMID: 36321117; PubMed Central PMCID: PMC9590333.
Castelnuovo B, Kamya M, Ratanshi RP, Kiragga AN, Nakanjako D. Longitudinal patients' cohorts for impactful research and HIV care at the Infectious Diseases Institute. Afr Health Sci. 2022 Aug;22(Spec Issue):11-21. doi: 10.4314/ahs.v22i2.4S. PubMed PMID: 36321114; PubMed Central PMCID: PMC9590324.
Muwonge H, Kasujja H, Niyonzima N, Atugonza C, Kasolo J, Lugaajju A, Nfambi J, Fred SL, Damani AM, Kimuli I, Zavuga R, Nakazzi F, Kigozi E, Nakanjako D, Kateete DP, Bwanga F. Unique circulating microRNA profiles in epidemic Kaposi's sarcoma. Noncoding RNA Res. 2022 Jun;7(2):114-122. doi: 10.1016/j.ncrna.2022.02.002. eCollection 2022 Jun. PubMed PMID: 35570854; PubMed Central PMCID: PMC9065625.
Otiti-Sengeri J, Andrew OB, Lusobya RC, Atukunda I, Nalukenge C, Kalinaki A, Mukisa J, Nakanjako D, Colebunders R. High COVID-19 Vaccine Acceptance among Eye Healthcare Workers in Uganda. Vaccines (Basel). 2022 Apr 14;10(4). doi: 10.3390/vaccines10040609. PubMed PMID: 35455358; PubMed Central PMCID: PMC9028371.
Kalinaki A, Muwonge H, Balagadde-Kambugu J, Mulumba Y, Ntende J, Ssali G, Nakiyingi L, Nakanjako D, Nalukenge C, Ampaire AM. Clinical presentation and outcomes in children with retinoblastoma managed at the Uganda Cancer Institute. J Cancer Epidemiol. 2022;2022:8817215. doi: 10.1155/2022/8817215. eCollection 2022. PubMed PMID: 35308301; PubMed Central PMCID: PMC8924608.
Mogaka JN, Sharma M, Temu T, Masyuko S, Kinuthia J, Osoti A, Zifodya J, Nakanjako D, Njoroge A, Otedo A, Page S, Farquhar C. Prevalence and factors associated with hypertension among adults with and without HIV in Western Kenya. PLoS One. 2022;17(1):e0262400. doi: 10.1371/journal.pone.0262400. eCollection 2022. PubMed PMID: 35007291; PubMed Central PMCID: PMC8746744.
Muwanguzi PA, Ngabirano TD, Kiwanuka N, Nelson LE, Nasuuna EM, Osingada CP, Nabunya R, Nakanjako D, Sewankambo NK. The Effects of Workplace-Based HIV Self-testing on Uptake of Testing and Linkage to HIV Care or Prevention by Men in Uganda (WISe-Men): Protocol for a Cluster Randomized Trial. JMIR Res Protoc. 2021 Nov 1;10(11):e25099. doi: 10.2196/25099. PubMed PMID: 34723826; PubMed Central PMCID: PMC8593794.
Nalubega S, Kyenkya J, Bagaya I, Nabukenya S, Ssewankambo N, Nakanjako D, Kiragga AN. COVID-19 may exacerbate the clinical, structural and psychological barriers to retention in care among women living with HIV in rural and peri-urban settings in Uganda. BMC Infect Dis. 2021 Sep 20;21(1):980. doi: 10.1186/s12879-021-06684-6. PubMed PMID: 34544389; PubMed Central PMCID: PMC8451386.
Sebabi FO, Okello WO, Nakubulwa F, Sempindu R, Driciru C, Nalukenge C, Mulinde B, Nakiyingi L, Nakanjako D, Ssali GN, Musika AA. Factors associated with delayed uptake of cataract surgery among adult patients at Mulago National Referral Hospital, Uganda. Afr Health Sci. 2021 Sep;21(3):1259-1265. doi: 10.4314/ahs.v21i3.36. PubMed PMID: 35222590; PubMed Central PMCID: PMC8843270.
Nabatanzi R, Bayigga L, Cose S, Canderan G, Rowland Jones S, Joloba M, Nakanjako D. Innate lymphoid cell dysfunction during long-term suppressive antiretroviral therapy in an African cohort. BMC Immunol. 2021 Aug 26;22(1):59. doi: 10.1186/s12865-021-00450-8. PubMed PMID: 34445953; PubMed Central PMCID: PMC8390268.Nakanjako D, Kendall D, Sewankambo NK, Razak MH, Oduor B, Odero T, Garcia P, Farquhar C. Building and Sustaining Effective Partnerships for Training the Next Generation of Global Health Leaders. Ann Glob Health. 2021;87(1):66. doi: 10.5334/aogh.3214. eCollection 2021. PubMed PMID: 34307069; PubMed Central PMCID: PMC8284501.
Kamulegeya A, Nakanjako D, Orem J, Mayanja-Kizza H. TRANSLATION AND DETERMINATION OF THE COMPREHENSIBILITY OF A LUGANDA VERSION OF ORAL MUCOSITIS DAILY QUESTIONNAIRE. East Afr Med J. 2021 Mar;98(3):3599-3607. Epub 2021 May 21. PubMed PMID: 36440467; PubMed Central PMCID: PMC9696668.
Gachuno O, Odero T, Seloilwe E, Urassa D, Tarimo E, Nakanjako D, Sewankambo N, Atanga NS, Halle-Ekane EG, Manabe Y, Hosey KN, Chapman SA, Wiebe DJ, Voss J, O'Malley G, Mashalla Y, Ndegwa M, Omogi J, Farquhar C, Wasserheit JN. AFYA BORA CONSORTIUM FELLOWSHIP: a journey of success in Global Health Leadership Training. Afr Health Sci. 2021 May;21(Suppl):i-ii. doi: 10.4314/ahs.v21i1.1S. PubMed PMID: 34447427; PubMed Central PMCID: PMC8367302.
Nasuuna E, Kigozi J, Muganzi A, Sewankambo N, Nakanjako D. Short report: knowledge and perceptions of health workers that strengthen adherence for paediatric and adolescent clients on the intensive adherence counselling program in Kampala, Uganda: a qualitative study. Afr Health Sci. 2021 May;21(Suppl):25-28. doi: 10.4314/ahs.v21i1.5S. PubMed PMID: 34447420; PubMed Central PMCID: PMC8367312.
Masyuko SJ, Page ST, Kinuthia J, Osoti AO, Polyak SJ, Otieno FC, Kibachio JM, Mogaka JN, Temu TM, Zifodya JS, Otedo A, Nakanjako D, Hughes JP, Farquhar C. Metabolic syndrome and 10-year cardiovascular risk among HIV-positive and HIV-negative adults: A cross-sectional study. Medicine (Baltimore). 2020 Jul 2;99(27):e20845. doi: 10.1097/MD.0000000000020845. PubMed PMID: 32629671; PubMed Central PMCID: PMC7337552.
Kinyanjui S, Fonn S, Kyobutungi C, Vicente-Crespo M, Bonfoh B, Ndungu T, Sewankambo NK, Djimde AA, Gaye O, Chirwa T, Musenge E, Elliot A, Nakanjako D, Chibanda D, Awandare G. Enhancing science preparedness for health emergencies in Africa through research capacity building. BMJ Glob Health. 2020 Jul;5(7). doi: 10.1136/bmjgh-2020-003072. PubMed PMID: 32636315; PubMed Central PMCID: PMC7342471.
Ndagire B, Mwesigwa CL, Ntuulo JM, Mayanja-Kizza H, Nakanjako D, Rwenyonyi CM. Dental Caries Pattern and Treatment Needs among Ugandan Adolescent Students: A Cross-Sectional Study. Int J Dent. 2020;2020:8135865. doi: 10.1155/2020/8135865. eCollection 2020. PubMed PMID: 32256595; PubMed Central PMCID: PMC7085876.
Ndagire B, Kutesa A, Ssenyonga R, Kiiza HM, Nakanjako D, Rwenyonyi CM. Prevalence, Severity and Factors Associated with Dental Caries Among School Adolescents in Uganda: A Cross-Sectional Study. Braz Dent J. 2020 Mar-Apr;31(2):171-178. doi: 10.1590/0103-6440202002841. PubMed PMID: 32556017; PubMed Central PMCID: PMC8346632
Kuteesa MO, Quaife M, Biraro S, Katumba KR, Seeley J, Kamali A, Nakanjako D. Acceptability and Predictors of Uptake of Anti-retroviral Pre-exposure Prophylaxis (PrEP) Among Fishing Communities in Uganda: A Cross-Sectional Discrete Choice Experiment Survey. AIDS Behav. 2019 Oct;23(10):2674-2686. doi: 10.1007/s10461-019-02418-7. PubMed PMID: 30734882.
Nabatanzi R, Bayigga L, Cose S, Rowland Jones S, Joloba M, Canderan G, Nakanjako D. Monocyte Dysfunction, Activation, and Inflammation After Long-Term Antiretroviral Therapy in an African Cohort. J Infect Dis. 2019 Sep 26;220(9):1414-1419. doi: 10.1093/infdis/jiz320. PubMed PMID: 31323092; PubMed Central PMCID: PMC6761975.
Muwanguzi PA, Nassuna LK, Voss JG, Kigozi J, Muganzi A, Ngabirano TD, Sewankambo N, Nakanjako D. Towards a definition of male partner involvement in the prevention of mother-to-child transmission of HIV in Uganda: a pragmatic grounded theory approach. BMC Health Serv Res. 2019 Aug 9;19(1):557. doi: 10.1186/s12913-019-4401-x. PubMed PMID: 31399088; PubMed Central PMCID: PMC6688339.
Kalanzi D, Mayanja-Kizza H, Nakanjako D, Mwesigwa CL, Ssenyonga R, Amaechi BT. Prevalence and factors associated with dental caries in patients attending an HIV care clinic in Uganda: a cross sectional study. BMC Oral Health. 2019 Jul 19;19(1):159. doi: 10.1186/s12903-019-0847-9. PubMed PMID: 31324242; PubMed Central PMCID: PMC6642521.
Ingabire PM, Semitala F, Kamya MR, Nakanjako D. Delayed Antiretroviral Therapy (ART) Initiation among Hospitalized Adults in a Resource-Limited Settings: A Challenge to the Global Target of ART for 90% of HIV-Infected Individuals. AIDS Res Treat. 2019;2019:1832152. doi: 10.1155/2019/1832152. eCollection 2019. PubMed PMID: 31057959; PubMed Central PMCID: PMC6463639.
Nabatanzi R, Bayigga L, Cose S, Rowland-Jones S, Canderan G, Joloba M, Nakanjako D. Aberrant natural killer (NK) cell activation and dysfunction among ART-treated HIV-infected adults in an African cohort. Clin Immunol. 2019 Apr;201:55-60. doi: 10.1016/j.clim.2019.02.010. Epub 2019 Feb 26. PubMed PMID: 30817998; PubMed Central PMCID: PMC6448528.
Nasuuna E, Kigozi J, Muwanguzi PA, Babirye J, Kiwala L, Muganzi A, Sewankambo N, Nakanjako D. Challenges faced by caregivers of virally non-suppressed children on the intensive adherence counselling program in Uganda: a qualitative study. BMC Health Serv Res. 2019 Mar 7;19(1):150. doi: 10.1186/s12913-019-3963-y. PubMed PMID: 30845951; PubMed Central PMCID: PMC6407183.
Bayigga L, Kateete DP, Anderson DJ, Sekikubo M, Nakanjako D. Diversity of vaginal microbiota in sub-Saharan Africa and its effects on HIV transmission and prevention. Am J Obstet Gynecol. 2019 Feb;220(2):155-166. doi: 10.1016/j.ajog.2018.10.014. Epub 2018 Oct 12. Review. PubMed PMID: 30321529.
Kalanzi D, Mayanja-Kizza H, Nakanjako D, Sewankambo NK. Extensive dental caries in a HIV positive adult patient on ART; case report and literature review. BMC Oral Health. 2018 Dec 7;18(1):205. doi: 10.1186/s12903-018-0675-3. Review. PubMed PMID: 30526565; PubMed Central PMCID: PMC6286575.
Zawedde-Muyanja S, Manabe YC, Sewankambo NK, Nakiyingi L, Nakanjako D. Xpert® MTB/RIF associated with improved treatment initiation among patients with smear-negative tuberculosis. Int J Tuberc Lung Dis. 2018 Dec 1;22(12):1475-1480. doi: 10.5588/ijtld.17.0460. PubMed PMID: 30606320; PubMed Central PMCID: PMC6306042.
Nasuuna E, Kigozi J, Babirye L, Muganzi A, Sewankambo NK, Nakanjako D. Low HIV viral suppression rates following the intensive adherence counseling (IAC) program for children and adolescents with viral failure in public health facilities in Uganda. BMC Public Health. 2018 Aug 22;18(1):1048. doi: 10.1186/s12889-018-5964-x. PubMed PMID: 30134880; PubMed Central PMCID: PMC6103875.
Buhikire K, Voss J, Kigozi J, Nyakato P, Ankunda N, Kalebbo B, Musiitwa M, Muganzi A, Sewankambo NK, Nakanjako D. Reaching the First 90 in Uganda: Predictors of Success in Contacting and Testing the Named Sexual Partners of HIV+ Index Clients in Kiboga District. AIDS Behav. 2018 Aug;22(8):2458-2467. doi: 10.1007/s10461-018-2137-y. PubMed PMID: 29754266.
Verma S, Du P, Nakanjako D, Hermans S, Briggs J, Nakiyingi L, Ellner JJ, Manabe YC, Salgame P. "Tuberculosis in advanced HIV infection is associated with increased expression of IFNγ and its downstream targets". BMC Infect Dis. 2018 May 15;18(1):220. doi: 10.1186/s12879-018-3127-4. PubMed PMID: 29764370; PubMed Central PMCID: PMC5952419.
Nabatanzi R, Cose S, Joloba M, Jones SR, Nakanjako D. Effects of HIV infection and ART on phenotype and function of circulating monocytes, natural killer, and innate lymphoid cells. AIDS Res Ther. 2018 Mar 15;15(1):7. doi: 10.1186/s12981-018-0194-y. Review. PubMed PMID: 29544508; PubMed Central PMCID: PMC5853105.
Otiti-Sengeri J, Colebunders R, Reynolds SJ, Muwonge M, Nakigozi G, Kiggundu V, Nalugoda F, Nakanjako D. Elevated inflammatory cytokines in aqueous cytokine profile in HIV-1 infected patients with cataracts in Uganda. BMC Ophthalmol. 2018 Jan 19;18(1):12. doi: 10.1186/s12886-018-0680-y. PubMed PMID: 29351788; PubMed Central PMCID: PMC5775574.
Osingada CP, Okuga M, Nabirye RC, Sewankambo NK, Nakanjako D. Disclosure of Parental HIV Status to Children: Experiences of Adults Receiving Antiretroviral Treatment at an Urban Clinic in Kampala, Uganda. AIDS Res Treat. 2017;2017:3458684. doi: 10.1155/2017/3458684. Epub 2017 Oct 25. PubMed PMID: 29209538; PubMed Central PMCID: PMC5676343.
Nakanjako D, Akena D, Kaye DK, Tumwine J, Okello E, Nakimuli A, Kambugu A, McCullough H, Mayanja-Kizza H, Kamya MR, Sewankambo NK. A need to accelerate health research productivity in an African University: the case of Makerere University College of Health Sciences. Health Res Policy Syst. 2017 Apr 21;15(1):33. doi: 10.1186/s12961-017-0196-6. Review. PubMed PMID: 28431554; PubMed Central PMCID: PMC5399829.
Monroe-Wise A, Mashalla Y, O'Malley G, Nathanson N, Seloilwe E, Gachuno O, Odero T, Nakanjako D, Sewankambo N, Tarimo E, Urassa D, Manabe YC, Chapman S, Voss JG, Wasserheit J, Farquhar C. Training tomorrow's leaders in global health: impact of the Afya Bora Consortium Fellowship on the careers of its alumni. BMC Med Educ. 2016 Sep 19;16(1):241. doi: 10.1186/s12909-016-0750-x. PubMed PMID: 27643589; PubMed Central PMCID: PMC5028919.
Nakanjako D, Kiragga AN, Musick BS, Yiannoutsos CT, Wools-Kaloustian K, Diero L, Oyaro P, Lugina E, Ssali JC, Kambugu A, Easterbrook P. Frequency and impact of suboptimal immune recovery on first-line antiretroviral therapy within the International Epidemiologic Databases to Evaluate AIDS in East Africa. AIDS. 2016 Jul 31;30(12):1913-22. doi: 10.1097/QAD.0000000000001085. PubMed PMID: 26959510; PubMed Central PMCID: PMC5438045.
Osingada CP, Okuga M, Nabirye RC, Sewankambo NK, Nakanjako D. Prevalence, barriers and factors associated with parental disclosure of their HIV positive status to children: a cross-sectional study in an urban clinic in Kampala, Uganda. BMC Public Health. 2016 Jul 11;16:547. doi: 10.1186/s12889-016-3235-2. PubMed PMID: 27401865; PubMed Central PMCID: PMC4940877.
Ousman K, Polomano RC, Seloilwe E, Odero T, Tarimo E, Mashalla YJ, Voss JG, O'Malley G, Chapman SA, Gachuno O, Manabe Y, Nakanjako D, Sewankambo N, Urassa D, Wasserheit JN, Wiebe DJ, Green W, Farquhar C. Interprofessional Fellowship Training for Emerging Global Health Leaders in Africa to Improve HIV Prevention and Care: The Afya Bora Consortium. J Assoc Nurses AIDS Care. 2016 May-Jun;27(3):331-43. doi: 10.1016/j.jana.2016.01.009. Epub 2016 Feb 4. PubMed PMID: 27086192; PubMed Central PMCID: PMC4834555.
Nakanjako D, Namagala E, Semeere A, Kigozi J, Sempa J, Ddamulira JB, Katamba A, Biraro S, Naikoba S, Mashalla Y, Farquhar C, Sewankambo N. Global health leadership training in resource-limited settings: a collaborative approach by academic institutions and local health care programs in Uganda. Hum Resour Health. 2015 Nov 18;13:87. doi: 10.1186/s12960-015-0087-2. PubMed PMID: 26581196; PubMed Central PMCID: PMC4650924.
Osingada CP, Nalwadda G, Ngabirano T, Wakida J, Sewankambo N, Nakanjako D. Nurses' knowledge in ethics and their perceptions regarding continuing ethics education: a cross-sectional survey among nurses at three referral hospitals in Uganda. BMC Res Notes. 2015 Jul 29;8:319. doi: 10.1186/s13104-015-1294-6. PubMed PMID: 26219840; PubMed Central PMCID: PMC4517354.
Nakiyingi L, Nonyane BA, Ssengooba W, Kirenga BJ, Nakanjako D, Lubega G, Byakika-Kibwika P, Joloba ML, Ellner JJ, Dorman SE, Mayanja-Kizza H, Manabe YC. Predictors for MTB Culture-Positivity among HIV-Infected Smear-Negative Presumptive Tuberculosis Patients in Uganda: Application of New Tuberculosis Diagnostic Technology. PLoS One. 2015;10(7):e0133756. doi: 10.1371/journal.pone.0133756. eCollection 2015. PubMed PMID: 26222142; PubMed Central PMCID: PMC4519276.
Kayima J, Nyakoojo W, Nakanjako D, Costa MA, Longenecker CT, Simon DI. Acute Spontaneous Coronary Artery Thrombosis as Initial Presentation of HIV Infection in a Young Man. Case Rep Cardiol. 2015;2015:342348. doi: 10.1155/2015/342348. Epub 2015 Mar 2. PubMed PMID: 25821605; PubMed Central PMCID: PMC4363571.
Nakanjako D, Ssinabulya I, Nabatanzi R, Bayigga L, Kiragga A, Joloba M, Kaleebu P, Kambugu AD, Kamya MR, Sekaly R, Elliott A, Mayanja-Kizza H. Atorvastatin reduces T-cell activation and exhaustion among HIV-infected cART-treated suboptimal immune responders in Uganda: a randomised crossover placebo-controlled trial. Trop Med Int Health. 2015 Mar;20(3):380-90. doi: 10.1111/tmi.12442. Epub 2015 Jan 6. PubMed PMID: 25441397; PubMed Central PMCID: PMC4529480.
Nakiyingi L, Ssengooba W, Nakanjako D, Armstrong D, Holshouser M, Kirenga BJ, Shah M, Mayanja-Kizza H, Joloba ML, Ellner JJ, Dorman SE, Manabe YC. Predictors and outcomes of mycobacteremia among HIV-infected smear- negative presumptive tuberculosis patients in Uganda. BMC Infect Dis. 2015 Feb 15;15:62. doi: 10.1186/s12879-015-0812-4. PubMed PMID: 25888317; PubMed Central PMCID: PMC4332438.
Geng EH, Neilands TB, Thièbaut R, Bwana MB, Nash D, Moore RD, Wood R, Zannou DM, Althoff KN, Lim PL, Nachega JB, Easterbrook PJ, Kambugu A, Little F, Nakigozi G, Nakanjako D, Kiggundu V, Ki Li PC, Bangsberg DR, Fox MP, Prozesky H, Hunt PW, Davies MA, Reynolds SJ, Egger M, Yiannoutsos CT, Vittinghoff EV, Deeks SG, Martin JN. CD41 T cell recovery during suppression of HIV replication: an international comparison of the immunological efficacy of antiretroviral therapy in North America, Asia and Africa. Int J Epidemiol. 2015 Feb;44(1):251-63. doi: 10.1093/ije/dyu271. PubMed PMID: 25859596; PubMed Central PMCID: PMC4339766.
Nakanjako D, Kaye D, Kambugu A, Okello E, Kamya M, Tumwine J, Mayanja-Kizza H. Structured career development for global health research in resource-limited settings: A pilot of career development series for faculty at Makerere university college of health sciences. Annals of Global Health. 2015; 81(1):64.
Nakanjako D, Kaye D, Kambugu A, Okello E, Kamya M, Tumwine J, Mayanja-Kizza H. Mentoring for sustainable in-country academic leadership in resource-limited settings. Annals of Global Health. 2015; 81(1):43.
Mugasha C, Kigozi J, Kiragga A, Muganzi A, Sewankambo N, Coutinho A, Nakanjako D. Intra-facility linkage of HIV-positive mothers and HIV-exposed babies into HIV chronic care: rural and urban experience in a resource limited setting. PLoS One. 2014;9(12):e115171. doi: 10.1371/journal.pone.0115171. eCollection 2014. PubMed PMID: 25546453; PubMed Central PMCID: PMC4278891.
Nabatanzi R, Bayigga L, Ssinabulya I, Kiragga A, Kambugu A, Olobo J, Joloba M, Kamya MR, Mayanja-Kizza H, Nakanjako D. Low antigen-specific CD4 T-cell immune responses despite normal absolute CD4 counts after long-term antiretroviral therapy an African cohort. Immunol Lett. 2014 Dec;162(2 Pt B):264-72. doi: 10.1016/j.imlet.2014.09.016. Epub 2014 Sep 26. PubMed PMID: 25263953; PubMed Central PMCID: PMC4537512.
Nakanjako D, Otiti-Sengeri J, Ssewanyana I, Nabatanzi R, Bayigga L, Kirimunda S, Joloba M, Manabe YC, Kambugu A, Colebunders R, Mayanja-Kizza H. CD4 T-cell activation and reduced regulatory T-cell populations are associated with early development of cataracts among HIV-infected adults in Uganda. Immunol Lett. 2014 Sep;161(1):44-9. doi: 10.1016/j.imlet.2014.04.011. Epub 2014 Apr 28. PubMed PMID: 24785834; PubMed Central PMCID: PMC4907352.
Ssinabulya I, Kayima J, Longenecker C, Luwedde M, Semitala F, Kambugu A, Ameda F, Bugeza S, McComsey G, Freers J, Nakanjako D. Subclinical atherosclerosis among HIV-infected adults attending HIV/AIDS care at two large ambulatory HIV clinics in Uganda. PLoS One. 2014;9(2):e89537. doi: 10.1371/journal.pone.0089537. eCollection 2014. PubMed PMID: 24586854; PubMed Central PMCID: PMC3938501.
Bayigga L, Nabatanzi R, Sekiziyivu PN, Mayanja-Kizza H, Kamya MR, Kambugu A, Olobo J, Kiragga A, Kirimunda S, Joloba M, Nakanjako D. High CD56++CD16- natural killer (NK) cells among suboptimal immune responders after four years of suppressive antiretroviral therapy in an African adult HIV treatment cohort. BMC Immunol. 2014 Jan 31;15:2. doi: 10.1186/1471-2172-15-2. PubMed PMID: 24483185; PubMed Central PMCID: PMC3915033.
Nakanjako D, Katamba A, Kaye DK, Okello E, Kamya MR, Sewankambo N, Mayanja-Kizza H. Doctoral training in Uganda: evaluation of mentoring best practices at Makerere university college of health sciences. BMC Med Educ. 2014 Jan 13;14:9. doi: 10.1186/1472-6920-14-9. PubMed PMID: 24410984; PubMed Central PMCID: PMC3897930.
Bazira J, Boum Y, Sempa J, Iramiot J, Nanjebe D, Sewankambo N, Nakanjako D. Trends in Antimicrobial Resistance of Staphylococcus aureus Isolated from Clinical Samples at Mbarara Regional Referral Hospital in Rural Uganda. British microbiology research journal. 2014; 4(10):1084-1091.
Kyeyune J, Nankinga Z, Groves S, Nakanjako D. Mentoring practices among health science students in low income countries; observations at Makerere university Kampala, Uganda. Journal of Education and Curriculum Development Research. 2014; 2(2):86-94.
Nakiyingi L, Bwanika JM, Kirenga B, Nakanjako D, Katabira C, Lubega G, Sempa J, Nyesiga B, Albert H, Manabe YC. Clinical predictors and accuracy of empiric tuberculosis treatment among sputum smear-negative HIV-infected adult TB suspects in Uganda. PLoS One. 2013;8(9):e74023. doi: 10.1371/journal.pone.0074023. eCollection 2013. PubMed PMID: 24040151; PubMed Central PMCID: PMC3765314.
Nakanjako D, Ssewanyana I, Nabatanzi R, Kiragga A, Kamya MR, Cao H, Mayanja-Kizza H. Impaired T-cell proliferation among HAART-treated adults with suboptimal CD4 recovery in an African cohort. BMC Immunol. 2013 Jun 20;14:26. doi: 10.1186/1471-2172-14-26. PubMed PMID: 23786370; PubMed Central PMCID: PMC3706234.
Tumwesigye BT, Nakanjako D, Wanyenze R, Akol Z, Sewankambo N. Policy development, implementation and evaluation by the AIDS control program in Uganda: a review of the processes. Health Res Policy Syst. 2013 Feb 23;11(1):7. doi: 10.1186/1478-4505-11-7. PubMed PMID: 23433339; PubMed Central PMCID: PMC3598343.
Nakanjako D, Mirembe FM, Beyeza-Kashesya J, Coutinho A. Scaling Up HIV/AIDS Care Among Women in Sub-Saharan Africa: Cross-Cultural Barriers. In: Women, Motherhood and Living with HIV/AIDS Netherlands: Springer Netherlands; 2013. Chapter 16; p.249-265.
Kyabayinze DJ, Achan J, Nakanjako D, Mpeka B, Mawejje H, Mugizi R, Kalyango JN, D'Alessandro U, Talisuna A, Jean-Pierre Vg. Parasite-based malaria diagnosis: are health systems in Uganda equipped enough to implement the policy?. BMC Public Health. 2012 Aug 24;12:695. doi: 10.1186/1471-2458-12-695. PubMed PMID: 22920954; PubMed Central PMCID: PMC3490993.
Semeere AS, Nakanjako D, Ddungu H, Kambugu A, Manabe YC, Colebunders R. Sub-optimal vitamin B-12 levels among ART-naïve HIV-positive individuals in an urban cohort in Uganda. PLoS One. 2012;7(7):e40072. doi: 10.1371/journal.pone.0040072. Epub 2012 Jul 2. PubMed PMID: 22768330; PubMed Central PMCID: PMC3388039.
Kyabayinze DJ, Asiimwe C, Nakanjako D, Nabakooza J, Bajabaite M, Strachan C, Tibenderana JK, Van Geetruyden JP. Programme level implementation of malaria rapid diagnostic tests (RDTs) use: outcomes and cost of training health workers at lower level health care facilities in Uganda. BMC Public Health. 2012 Apr 20;12:291. doi: 10.1186/1471-2458-12-291. PubMed PMID: 22519958; PubMed Central PMCID: PMC3433367.
Nakanjako D, Byakika-Kibwika P, Kintu K, Aizire J, Nakwagala F, Luzige S, Namisi C, Mayanja-Kizza H, Kamya MR. Mentorship needs at academic institutions in resource-limited settings: a survey at Makerere University College of Health Sciences. BMC Med Educ. 2011 Jul 29;11:53. doi: 10.1186/1472-6920-11-53. PubMed PMID: 21801406; PubMed Central PMCID: PMC3170866.
Nakanjako D, Kiragga AN, Castelnuovo B, Kyabayinze DJ, Kamya MR. Low prevalence of Plasmodium falciparum antigenaemia among asymptomatic HAART-treated adults in an urban cohort in Uganda. Malar J. 2011 Mar 22;10:66. doi: 10.1186/1475-2875-10-66. PubMed PMID: 21426579; PubMed Central PMCID: PMC3071332.
Nakanjako D, Ssewanyana I, Mayanja-Kizza H, Kiragga A, Colebunders R, Manabe YC, Nabatanzi R, Kamya MR, Cao H. High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort. BMC Infect Dis. 2011 Feb 8;11:43. doi: 10.1186/1471-2334-11-43. PubMed PMID: 21299909; PubMed Central PMCID: PMC3065409.Nakanjako D. Efficient HIV/AIDS care in resource-limited settings Germany: VDM; 2011. 179p.
Nakanjako D, Mayanja-Kizza H, Ouma J, Wanyenze R, Mwesigire D, Namale A, Ssempiira J, Senkusu J, Colebunders R, Kamya MR. Tuberculosis and human immunodeficiency virus co-infections and their predictors at a hospital-based HIV/AIDS clinic in Uganda. Int J Tuberc Lung Dis. 2010 Dec;14(12):1621-8. PubMed PMID: 21144249.
Kiragga AN, Castelnuovo B, Nakanjako D, Manabe YC. Baseline severe anaemia should not preclude use of zidovudine in antiretroviral-eligible patients in resource-limited settings. J Int AIDS Soc. 2010 Nov 3;13:42. doi: 10.1186/1758-2652-13-42. PubMed PMID: 21047391; PubMed Central PMCID: PMC2991285.
Kyabayinze DJ, Asiimwe C, Nakanjako D, Nabakooza J, Counihan H, Tibenderana JK. Use of RDTs to improve malaria diagnosis and fever case management at primary health care facilities in Uganda. Malar J. 2010 Jul 12;9:200. doi: 10.1186/1475-2875-9-200. PubMed PMID: 20624312; PubMed Central PMCID: PMC2914063.
Nakanjako D, Colebunders R, Coutinho AG, Kamya MR. Strategies to optimize HIV treatment outcomes in resource-limited settings. AIDS Rev. 2009 Oct-Dec;11(4):179-89. Review. PubMed PMID: 19940945.
Lule JR, Mermin J, Awor A, Hughes P, Kigozi A, Wafula W, Nakanjako D, Kaharuza F, Downing R, Quick R. Aetiology of diarrhoea among persons with HIV and their family members in rural Uganda: a community-based study. East Afr Med J. 2009 Sep;86(9):422-9. doi: 10.4314/eamj.v86i9.54164. PubMed PMID: 21644412.
Nassali M, Nakanjako D, Kyabayinze D, Beyeza J, Okoth A, Mutyaba T. Access to HIV/AIDS care for mothers and children in sub-Saharan Africa: adherence to the postnatal PMTCT program. AIDS Care. 2009 Sep;21(9):1124-31. doi: 10.1080/09540120802707467. PubMed PMID: 20024771.
Nakanjako D, Kiragga A, Ibrahim F, Castelnuovo B, Kamya MR, Easterbrook PJ. Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on antiretroviral therapy (ART) in sub-Saharan Africa: frequency and clinical significance. AIDS Res Ther. 2008 Oct 28;5:23. doi: 10.1186/1742-6405-5-23. PubMed PMID: 18957083; PubMed Central PMCID: PMC2605744.
Nakanjako D, Kamya M, Daniel K, Mayanja-Kizza H, Freers J, Whalen C, Katabira E. Acceptance of routine testing for HIV among adult patients at the medical emergency unit at a national referral hospital in Kampala, Uganda. AIDS Behav. 2007 Sep;11(5):753-8. doi: 10.1007/s10461-006-9180-9. Epub 2006 Nov 10. PubMed PMID: 17096199.
Nakanjako D, Kyabayinze DJ, Mayanja-Kizza H, Katabira E, Kamya MR. Eligibility for HIV/AIDS treatment among adults in a medical emergency setting at an urban hospital in Uganda. Afr Health Sci. 2007 Sep;7(3):124-8. doi: 10.5555/afhs.2007.7.3.124. PubMed PMID: 18052863; PubMed Central PMCID: PMC2269717.
Lule JR, Mermin J, Ekwaru JP, Malamba S, Downing R, Ransom R, Nakanjako D, Wafula W, Hughes P, Bunnell R, Kaharuza F, Coutinho A, Kigozi A, Quick R. Effect of home-based water chlorination and safe storage on diarrhea among persons with human immunodeficiency virus in Uganda. Am J Trop Med Hyg. 2005 Nov;73(5):926-33. PubMed PMID: 16282305.
Mermin J, Lule J, Ekwaru JP, Malamba S, Downing R, Ransom R, Kaharuza F, Culver D, Kizito F, Bunnell R, Kigozi A, Nakanjako D, Wafula W, Quick R. Effect of co-trimoxazole prophylaxis on morbidity, mortality, CD4-cell count, and viral load in HIV infection in rural Uganda. Lancet. 2004 Oct 16-22;364(9443):1428-34. doi: 10.1016/S0140-6736(04)17225-5. PubMed PMID: 15488218.
Grants,Awards and Certifications
Grants :
Ongoing Grants
Capacity building for vaccine research in sub-Saharan Africa, funded by the Alliance of Research Universities in Africa (ARUA):
Role: Principal Investigator
Exploring the feasibility of a population cohort to facilitate long-term studies on risk factors for non-communicable diseases in Uganda.
Role: Co-investigator
Proposal Titled Use of Machine Learning as a Prognosis Predictive Model to Guide Clinical Decision Making on the Infectious Diseases Unit at Kiruddu National Referral Hospital. Role: Co-Investigator
NURTURE: Research Training and Mentorship for Career Development of Junior Faculty at Makerere University College of Health Sciences: D43 TW010132-01 PI Nelson Sewankambo: Role: Mentor 08/31/2015 – 07/31/2022:
Title: Innate immune system recovery and immune aging during long-term antiretroviral therapy: Role: Principal Investigator
Project title: “Recovery of Innate lymphoid Cells and Natural killer cell dysfunction after long term Anti-Retroviral Therapy (ART) in an African Cohort”, funded by the alliance for global health and Science, University of California Berkeley. Role: Principal Investigator
Prime award number SP30A102775727 Subaward no: 761501 Project title: Acceptability of Pre-exposure Prophylaxis (PrEP) and factors likely to influence its uptake among fisherfolk in Uganda: A discrete choice experiment. Role: Principal investigator 1/06/ 2016-31/12/2017
Factors associated with failure of return for infant HIV test results in central Uganda: Parental disclosure of their HIV status to their children: Prevalence, Associated factors and Parents’ experiences. Role: Principal investigator 1/06/ 2016-31/12/ Role: Co-investigator
1/06/ 2016-31/12/2017
Improving uptake into psychosocial support structures for HIV infected pregnant women at public hospitals in Uganda: a randomized trial of a psychosocial assessment guide intervention. Role: Principal-investigator 1/06/ 2016-31/12/2017
Grand Challenge Canada RS-0145, Use of atorvastatin as adjuvant therapy among HAART suboptimal immune responders:
Role: Principal investigator
R25TW009343 subaward 7186SC.Capacity building for mentoring at the Infectious Diseases Institute at Makerere University, Kampala, Uganda: Clayton-Dedonder Global Health Mentorship Fellowship. Role: Principal investigator
Awards & Prizes :
Awards
2013: \Merle A. Sande Health Leadership Award in recognition of the contribution my work on optimizing HIV treatment outcomes and reducing HIV-associated morbidity and mortality in sub-Saharan Africa
2022: The World Academy of Science (TWAS) Abdool Karim award in recognition of my clinical and translational studies on mechanisms of immune activation, inflammation, and recovery of innate and adaptive immunity during chronic HIV infection and antiretroviral in sub-Saharan Africa.
2016: International scholarship award for the conference on Retroviruses and Opportunistic infections (CROI), 2016.
2015: CUGH Conference Travel Scholarship: One of ten awards in 2015 to individuals traveling from low income countries to make an abstract presentation at the CUGH conference in Boston, March 26 – 28, 2015.
2015: The Global Health Travel Award funded by the Bill & Melinda Gates Foundation. One of 29 awards (out of 161 applicants globally) to attend the Keystone Symposium: E1, Mechanisms of HIV Persistence: Implications for a Cure to be held at the Boston Park Plaza in Boston, USA on April 26 – May 1, 2015.
