Dr. Haghighi is the Director of International Center for Genetic Disease at Brigham and Woemen's Hospital, Harvard Medical School. He is an American Board certified geneticist and clinician scientist, an Assistant Professor of Medicine at the Department of Medicine, Harvard Medical School. Dr. Haghighi has served as the Lead Clinical Molecular Geneticist at Harvard Brigham Genomic Medicine, an integrated clinical and research program that uses genomics and biological validation to (1) discover genetic causes of undiagnosed monogenic diseases, and (2) to devise improved or novel diagnostics or treatments.

He completed his studies at University of Oxford, and Harvard Medical School, and was based at the Wellcome Trust Centre for Human Genetics before moving to Harvard.  His research focuses on clinical and genetic investigation of inherited diseases and discovering novel disease genes, using a combination of genomic technologies such as whole genome sequencing, and RNAseq. He also works on translating the research discoveries into better diagnostics and improved management strategies, and opportunities for developing novel therapeutics to treat diseases.

Dr. Haghighi is the President of Advancement Initiative for Medicine and Science (AIMS), a global foundation dedicated to the advancement of medicine and science around the world. AIMS brings together world-class academics and physicians (from the US and Europe), and work with governments and universities in partner countries in order to develop and implement different knowledge and expertise transfer programs with the aim of building capacity in medicine and surgery there.